38776-76-0Relevant articles and documents
Preparation of 9-hydroxy grayanotoxin derivatives and their acute toxicity in mice.
Terai, Tadamasa,Osakabe, Kanehiro,Katai, Masaaki,Sakaguchi, Ken-Ichi,Narama, Isao,Matsuura, Tetsuro,Katakawa, Jun'ichi,Tetsumi, Tadahiro
, p. 351 - 353 (2007/10/03)
Novel 9alpha and 9beta-hydroxy grayanotoxin II derivatives were prepared by photo-sensitized oxygenation of iso-grayanotoxin II and oxidation of grayanotoxin II tetraacetate with selenium dioxide respectively. The lethal dosage of 9alpha and 9beta-hydroxy grayanotoxin II were lower than that of grayanotoxin II. In addition, the lethal dosage of 9beta-hydroxy-dihydro grayanotoxin II was higher than that of dihydro grayanotoxin II.