388-21-6

Basic information

• Product Name: (2-benzoylphenyl)(4-fluorophenyl)methanone
• CAS NO: 388-21-6
• Molecular Formula: C₂₀H₁₃FO₂
• Molecular Weight: 304.3144
• Mol File: 388-21-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 488.1°C at 760 mmHg
• Flash Point: 182.9°C
• Density: 1.217g/cm³
• Vapor Pressure: 1.12E-09mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: (2-benzoylphenyl)(4-fluorophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-benzoylphenyl)(4-fluorophenyl)methanone(388-21-6)
• EPA Substance Registry System: (2-benzoylphenyl)(4-fluorophenyl)methanone(388-21-6)

Safety Data

• Hazardous Substances Data: 388-21-6(Hazardous Substances Data)

Usage

Description

(2-Benzoylphenyl)(4-fluorophenyl)methanone is a ketone compound composed of a benzoylphenyl group and a fluorophenyl group connected to a methanone moiety. It has the molecular formula C20H15FO and has been studied for its potential pharmaceutical applications, such as in the development of new drugs and medications. Its properties and potential uses make it a valuable compound for further research and development in the field of medicinal chemistry.

Uses

Used in Pharmaceutical Industry:
(2-Benzoylphenyl)(4-fluorophenyl)methanone is used as a pharmaceutical compound for its potential applications in the development of new drugs and medications. Its unique structure and properties may contribute to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Used in Medicinal Chemistry Research:
(2-Benzoylphenyl)(4-fluorophenyl)methanone is used as a research compound in medicinal chemistry for exploring its potential applications and properties. Its structure and characteristics may provide valuable insights into the design and synthesis of new pharmaceutical agents, contributing to the advancement of drug discovery and development.

Upstream product

• 71-43-2 benzene 
• 22115-41-9 2-(bromomethyl)benzonitrile 
• 56153-61-8 2-benzyl-benzonitrile 
• 7607-49-0 2-(4-fluoro-benzyl)-benzonitrile 
• 368-00-3 1-chloro-2-(4-fluorobenzyl)benzene 
• 394-76-3 2-(4-fluoro-benzyl)-benzophenone 

Relevant articles and documents

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere via N-H imines as an intramolecular directing group

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere was developed starting from carbonitriles and Grignard reagents via N-H imine intermediates. The present process is characterized by the following two-step sequence in a one-pot manner: (1) addition of Grignard reagents to carbonitriles to form N-H imines and (2) benzylic C-H oxygenation (C=O bond formation) triggered by 1,5-hydrogen atom transfer with transient iminyl copper species.