3883-39-4

Basic information

• Product Name: 5-METHYL-2-VINYLPYRIDINE
• Synonyms: Pyridine, 2-ethenyl-5-methyl-
• CAS NO: 3883-39-4
• Molecular Formula: C₈H₉N
• Molecular Weight: 119.16
• Mol File: 3883-39-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 100-102.5 °C(Press: 46 Torr)
• Appearance: /
• Density: 0.954±0.06 g/cm3(Predicted)
• PKA: 5.09±0.10(Predicted)
• CAS DataBase Reference: 5-METHYL-2-VINYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-2-VINYLPYRIDINE(3883-39-4)
• EPA Substance Registry System: 5-METHYL-2-VINYLPYRIDINE(3883-39-4)

Safety Data

• Hazardous Substances Data: 3883-39-4(Hazardous Substances Data)

Usage

General Description

5-Methyl-2-vinylpyridine is a chemical compound with the molecular formula C8H9N. It is a toxic and flammable liquid that is used in various industrial processes, including as a building block in the synthesis of pharmaceuticals and agrochemicals. 5-METHYL-2-VINYLPYRIDINE is a member of the pyridine chemical family and is characterized by its strong, unpleasant odor. It is a potentially hazardous material that should be handled with care, as exposure to 5-methyl-2-vinylpyridine can cause irritation to the skin, eyes, and respiratory system. Additionally, prolonged or repeated exposure to this chemical may have harmful effects on human health. Therefore, it is important to use appropriate safety measures and protective equipment when working with 5-methyl-2-vinylpyridine.

Upstream product

• 3510-66-5 2-Bromo-5-methylpyridine 
• 4985-92-6 5-methylpicolinaldehyde 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 92988-08-4 trivinylboroxin 
• 7486-35-3 tri-n-butyl(vinyl)tin 

Downstream Products

• 1257521-42-8 2-(1-benzyl-pyrrolidin-3-yl)-5-methyl-pyridine 
• 1527527-91-8 N-(2-(5-methylpyridin-2-yl)ethyl)benzenesulfonamide 
• 132554-28-0 3-(5-Methyl-pyridin-2-yl)-1-phenyl-propan-1-one 
• 132554-32-6 1,5-Dimethyl-2-(2-benzoylethyl)pyridinium iodide 
• 136401-80-4 2-Imino-5-{4-[2-(5-methyl-pyridin-2-yl)-ethylsulfanyl]-benzyl}-thiazolidin-4-one 
• 136401-59-7 5-{4-[2-(5-Methyl-pyridin-2-yl)-ethylsulfanyl]-benzyl}-thiazolidine-2,4-dione 
• 136401-90-6 4-[2-(5-Methyl-pyridin-2-yl)-ethylsulfanyl]-phenylamine 

Relevant articles and documents

N2Phos - an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki-Miyaura cross couplings in water

A new biaryl phosphine-containing ligand from an active palladium catalyst for ppm level Suzuki-Miyaura couplings, enabled by an aqueous micellar reaction medium. A wide array of functionalized substrates including aryl/heteroaryl bromides are amenable, as are, notably, chlorides. The catalytic system is both general and highly effective at low palladium loadings (1000-2500 ppm or 0.10-0.25 mol%). Density functional theory calculations suggest that greater steric congestion in N2Phos induces increased steric crowding around the Pd center, helping to destabilize the 2?:?1 ligand-Pd(0) complex more for N2Phos than for EvanPhos (and less bulky ligands), and thereby favoring formation of the 1?:?1 ligand-Pdocomplex that is more reactive in oxidative addition to aryl chlorides.

Cobalt-catalyzed addition of styrylboronic acids to 2-vinylpyridine derivatives

Treatment of 2-vinyl nitrogen-containing heteroaromatic compounds with styrylboronic acid in the presence of a cobalt catalyst and a base results in an addition reaction to afford the corresponding 4-phenyl-3-butenyl heteroarenes. The adjacent nitrogen atom is essential for the promotion of the reaction because the nitrogen accelerates the addition of the styryl cobalt species, generated by transmetalation, onto the vinyl group. The reaction represents a rare example of cobalt catalysis in the reactions of organoboronic acids. Accelerated addition: Treatment of 2-vinylpyridine derivatives with styrylboronic acids under cobalt catalysis results in addition reactions. This represents a rare example of the cobalt-catalyzed reaction of organoboronic acids. Cobalt shows catalytic activity similar to rhodium, and catalyzes an unprecedented assembly of organoboronic acids and activated alkenes. Copyright

2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774

The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted;R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocycl