38849-38-6

Basic information

• Product Name: Benzaldehyde, 2-bromo-4-methoxy-3-(phenylmethoxy)-
• CAS NO: 38849-38-6
• Molecular Formula: C15H13BrO3
• Molecular Weight: 321.17
• Mol File: 38849-38-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-bromo-4-methoxy-3-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-bromo-4-methoxy-3-(phenylmethoxy)-(38849-38-6)
• EPA Substance Registry System: Benzaldehyde, 2-bromo-4-methoxy-3-(phenylmethoxy)-(38849-38-6)

Safety Data

• Hazardous Substances Data: 38849-38-6(Hazardous Substances Data)

Upstream product

• 621-59-0 isovanillin 
• 2973-58-2 2-bromoisovanillin 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 
• 135586-23-1 2,2′-diformyl-5,5′-dimethoxy-6,6′-bis(phenylmethoxy)biphenyl 

Relevant articles and documents

First total synthesis of the pavine alkaloid (±)-neocaryachine and its optical resolution

The first total synthesis of (±)-neocaryachine (1) was achieved using a radical cyclization to produce the dibenzo-9-azabicyclo[3.3.1]nonane pavine skeleton, following a Bischler-Napieralski reaction to construct an intermediate benzylisoquinoline. The resulting racemic mixture was separated by chiral column chromatography to provide pure (+)- and (?)-1.

Improved synthesis of nigricanin

An ellagic acid-related natural product, nigricanin (1), was synthesized via the Ullmann coupling reaction of 2-bromo-3,4-dialkoxybenzaldehyde (4) followed by the Cannizzaro reaction for desymmetrization of the symmetric biaryl compound (5). Compared to o

With anti-tumor activity of a biphenyl amide compound and its preparation method and application

The invention discloses a biphenyl amide compound with antitumor activity as well as a preparation method and application thereof. The structural formula of the compound is shown in the specification, wherein in the structural formula, R1 is hydrogen or halogen; R2 is alkoxy with carbon number of 1-4; the terminal of R2 is replaced by tert-amido; R2 is linked to the para-position of amide via an oxygen atom. The compound has good tumor cell inhibiting activity in vitro and can be used for preparing antitumor drugs, especially anti-hepatoma drugs and anti-breast cancer drugs. The preparation method of the biphenyl amide compound, provided by the invention, has the advantages that the raw materials are accessible, the reaction conditions are mild, the reaction process is simple to operate, and the used reagent is cheap.