388569-21-9

Basic information

• Product Name: 2(1H)-Quinolinone, 3-[4,5-dihydro-4-[(2-hydroxyphenyl)methylene]-5-oxo-1H-pyrazol-3-yl]-4- hydroxy-1-methyl-
• CAS NO: 388569-21-9
• Molecular Formula: C20H15N3O4
• Molecular Weight: 361.357
• Mol File: 388569-21-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(1H)-Quinolinone, 3-[4,5-dihydro-4-[(2-hydroxyphenyl)methylene]-5-oxo-1H-pyrazol-3-yl]-4- hydroxy-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinolinone, 3-[4,5-dihydro-4-[(2-hydroxyphenyl)methylene]-5-oxo-1H-pyrazol-3-yl]-4- hydroxy-1-methyl-(388569-21-9)
• EPA Substance Registry System: 2(1H)-Quinolinone, 3-[4,5-dihydro-4-[(2-hydroxyphenyl)methylene]-5-oxo-1H-pyrazol-3-yl]-4- hydroxy-1-methyl-(388569-21-9)

Safety Data

• Hazardous Substances Data: 388569-21-9(Hazardous Substances Data)

Upstream product

• 1375007-11-6 4-hydroxy-1-methyl-3-[(2-oxo-2H-chromen-3-yl)carbonyl]quinolin-2(1H)-one 

Relevant articles and documents

Substituted quinolinones. Part 17: Some nucleophilic reactions with 4-hydroxy-1-methyl-3-[(2-oxo-2H-chromen-3-yl)carbonyl]quinolin- 2(1H)-one

The reactivity of 4-hydroxy-1-methyl-3-[(2-oxo-2H-chromen-3-yl)carbonyl]- quinolin-2(1H)-one (2), as a new asymmetric diheterocyclic ketone, towards different nucleophilic reagents, was examined. The reaction of the ketone 2 with hydrazine led to pyrazolinone 5, and excess of hydrazine pyrazolinopyrazole 7 was obtained. Treatment of the ketone 2 with 2,2-dimethoxyethanamine gave pyrrolocoumarin 12, while cyanoguanidine afforded pyrimidinone 15. Under PTC conditions, the ketone 2 was reacted with chloroacetonitrile, diethyl malonate, ethyl cyanoacetate, malononitrile, and cyanoacetamide to give coumarinyl furoquinoline 18, pyranoquinolines 20a, 20b, 21, and benzonaphthyridine 22, respectively. Indian Academy of Sciences.