388573-73-7

Basic information

• Product Name: 2H-Pyran-3-carbonitrile, 6-(4-chlorophenyl)-2-oxo-4-(4-phenyl-1-piperazinyl)-
• CAS NO: 388573-73-7
• Molecular Formula: C22H18ClN3O2
• Molecular Weight: 391.857
• Mol File: 388573-73-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-3-carbonitrile, 6-(4-chlorophenyl)-2-oxo-4-(4-phenyl-1-piperazinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-3-carbonitrile, 6-(4-chlorophenyl)-2-oxo-4-(4-phenyl-1-piperazinyl)-(388573-73-7)
• EPA Substance Registry System: 2H-Pyran-3-carbonitrile, 6-(4-chlorophenyl)-2-oxo-4-(4-phenyl-1-piperazinyl)-(388573-73-7)

Safety Data

• Hazardous Substances Data: 388573-73-7(Hazardous Substances Data)

Upstream product

• 99-91-2 para-chloroacetophenone 
• 92-54-6 4-phenyl-1-piperazine 
• 94835-61-7 6-(4-chlorophenyl)-3-cyano-4-methylsulfanyl-2H-pyran-2-one 

Relevant articles and documents

Substituent dependent regioselective synthesis of pyranopyrandiones and 1,2-teraryls from 2H-pyran-2-ones

The one-pot substituent-directed regioselective synthesis of 1,7-diaryl-2-methyl-4H,5H-pyrano[3,4-c]pyran-4,5-diones 3 as the major and 3,4-diaryl-2-methyl-6-methylsulfanylbenzonitriles 4 as the minor products has been delineated through ring transformation of suitably functionalized 2H-pyran-2-ones 1 with aryl acetones 2. Under similar reaction conditions, 6-aryl-4-sec-amino-2H-pyran-2-ones 5 led, regioselectively, to 3,4-diaryl-2-methyl-6-sec-aminobenzonitriles 6.

Synthesis, spectral characterization and photophysical studies of tetrahydroquinolines

A metal-free, ultrasound-assisted, fast synthesis of fluorescent N-Boc-protected 1,2,3,4–tetrahydroquinolines 9a-p is described through carbanion-induced ring transformation of 6-aryl-2H-pyran-2-ones 7 with tert?butyl 3-oxopiperidine-1-carboxylate 8 under