388575-18-6Relevant articles and documents
[1,2,4]Triazino[4,3-a]benzimidazole acetic acid derivatives: A new class of selective aldose reductase inhibitors
Da Settimo,Boldrini,Primofiore,Da Settimo,La Motta,Taliani,Simorini,Novellino,Greco,Lavecchia
, p. 4359 - 4369 (2007/10/03)
Acetic acid derivatives of [1,2,4]triazino[4,3-a]benzimidazole (TBI) were synthesized and tested in vitro and in vivo as a novel class of aldose reductase (ALR2) inhibitors. Compound 3, (10-benzyl[1,2,4]triazino[4,3-a]benzimidazol-3,4(10H)-dion-2-yl)aceti