38862-25-8 Usage
Description
N-Succinimidyl Methacrylate, also known as Methacrylic acid N-hydroxysuccinimide ester, is a chemical compound that serves as a versatile crosslinking agent and functional monomer in various applications. It possesses a reactive N-hydroxysuccinimide (NHS) ester group, which allows it to readily react with primary amines, making it a valuable tool for bioconjugation and the formation of covalent bonds.
Uses
Used in Bioconjugation Applications:
N-Succinimidyl Methacrylate is used as a crosslinking agent for bioconjugation with proteins. The NHS ester group reacts with primary amines on the protein surface, forming stable amide bonds and allowing for the attachment of various functional groups or other biomolecules.
Used in Water Treatment Industry:
N-Succinimidyl Methacrylate is used as a monomer in the fabrication of a bionanocomposite for the removal of chromium from water. The bionanocomposite can selectively bind and remove chromium ions, providing an efficient and eco-friendly solution for water purification.
Used in Polymer Science:
N-Succinimidyl Methacrylate can be copolymerized by reversible addition fragmentation chain transfer (RAFT) polymerization. This allows for the creation of well-defined polymers with controlled molecular weights and architectures, which can be tailored for specific applications.
Used in Temperature-Sensitive Polymers:
N-Succinimidyl Methacrylate can be copolymerized with poly(N-isopropylacrylamide) to create temperature-sensitive polymers. These polymers exhibit a lower critical solution temperature (LCST) behavior, which allows them to undergo reversible phase transitions in response to temperature changes. This property can be utilized in various applications, such as drug delivery systems, where the release of a drug can be triggered by a change in temperature.
Used in Immunoassay Applications:
N-Succinimidyl Methacrylate is used as a functional monomer in the development of immunoassay platforms. The reactive NHS ester group allows for the covalent attachment of antibodies or other recognition elements, enabling the specific detection and quantification of target analytes.
Used in Catalyst Recovery:
N-Succinimidyl Methacrylate can be used in the design of catalyst recovery systems. The reactive NHS ester group can be used to attach catalysts to a support material, allowing for their easy recovery and reuse in various chemical reactions.
Used in Drug Delivery Systems:
N-Succinimidyl Methacrylate can be incorporated into drug delivery systems, such as hydrogels or nanoparticles, to enable the controlled release of therapeutic agents. The reactive NHS ester group can be used to attach drugs or other bioactive molecules, allowing for their stable incorporation into the delivery system and subsequent release under specific conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 38862-25-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,8,6 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 38862-25:
(7*3)+(6*8)+(5*8)+(4*6)+(3*2)+(2*2)+(1*5)=148
148 % 10 = 8
So 38862-25-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3
38862-25-8Relevant articles and documents
Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same
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, (2011/01/05)
The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents.
