38917-36-1

Basic information

• Product Name: 1,3,4-Thiadiazol-2-amine, N-(1-methylethyl)-
• Synonyms: 1,3,4-Thiadiazol-2-amine, N-(1-methylethyl)-
• CAS NO: 38917-36-1
• Molecular Formula: C5H9N3S
• Molecular Weight: 143.21
• Mol File: 38917-36-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 109-110 °C
• Boiling Point: 214.0±23.0 °C(Predicted)
• Appearance: /
• Density: 1.211±0.06 g/cm3(Predicted)
• PKA: 2.34±0.10(Predicted)
• CAS DataBase Reference: 1,3,4-Thiadiazol-2-amine, N-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Thiadiazol-2-amine, N-(1-methylethyl)-(38917-36-1)
• EPA Substance Registry System: 1,3,4-Thiadiazol-2-amine, N-(1-methylethyl)-(38917-36-1)

Safety Data

• Hazardous Substances Data: 38917-36-1(Hazardous Substances Data)

Usage

Chemical class

Organic compound known as thiadiazoles

Common use

Building block for the synthesis of various drugs and pharmaceutical compounds

Potential applications

Anti-fungal and anti-bacterial agent

Research focus

Therapeutic applications

Structural components

Thiadiazole ring with an amine group

Substitution

N-(1-methylethyl) adds a tertiary amine group to the molecule

Influence of substitution

Can affect reactivity and biological activity

Importance

Potential applications in pharmaceutical and medical fields

Upstream product

• 13431-36-2 4-isopropyl-3-thiosemicarbazide 
• 122-51-0 orthoformic acid triethyl ester 

Relevant articles and documents

Mesoionic purinone analogs. 7. In vitro antibacterial activity of mesoionic 1,3,4 thiadiazolo[3,2 a]pyrimidine 5,7 diones

The discovery of in vitro antibacterial activity of mesoionic thiazolo[3,2-αDpyrimidine-5,7-diones and mesoionic 1,3,4-thiadiazolo[3,2-α]pyrimidine-5,7-diones has been recently reported. These compounds are members of a large, virtually unknown, class of mesoionic structures, termed mesoionic purinone analogs, which are isoelectronic and isosteric to the purinones: xanthine, hypoxanthine, or purin-2-one. The formulation, classification, and quantum chemical study of a large number of these heterocyclic structures have been described. A series of alkyl and aryl substituted mesoionic 1,3,4-thiadiazolo[3,2-α]pyrimidine-5,7-diones, mesoionic xanthine analogs, was prepared and examined for antibacterial activity in order to develop structure activity relationships leading to more active derivatives.