390360-97-1 Usage
General Description
2-hydroxy-5-iodonicotinic acid is a chemical compound with the molecular formula C6H4INO3. It is a derivative of nicotinic acid and contains a hydroxyl group and an iodine atom attached to the pyridine ring. 2-hydroxy-5-iodonicotinic acid is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential biological activities, including its anti-inflammatory and antioxidant properties. Additionally, 2-hydroxy-5-iodonicotinic acid has been investigated for its potential use in the synthesis of metal-organic frameworks and other coordination compounds due to its strong coordination ability with metal ions. Overall, this compound has several important applications in both the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 390360-97-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,0,3,6 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 390360-97:
(8*3)+(7*9)+(6*0)+(5*3)+(4*6)+(3*0)+(2*9)+(1*7)=151
151 % 10 = 1
So 390360-97-1 is a valid CAS Registry Number.
390360-97-1Relevant articles and documents
Orally active ghrelin receptor inverse agonists and their actions on a rat obesity model
Takahashi, Bitoku,Funami, Hideaki,Iwaki, Takehiko,Maruoka, Hiroshi,Shibata, Makoto,Koyama, Makoto,Nagahira, Asako,Kamiide, Yoshiyuki,Kanki, Satomi,Igawa, Yoshiyuki,Muto, Tsuyoshi
, p. 4792 - 4803 (2015/08/03)
A series of 2-alkylamino nicotinamide analogs was prepared as orally active ghrelin receptor (ghrelinR) inverse agonists. Starting from compound 1, oral bioavailability was improved by modifying metabolically unstable sites and reducing molecular weight. Brain-permeable compound 33 and compound 24 with low brain permeability were tested in rat models of obesity; 30 mg/kg of compound 33 suppressed weight gain. PK/PD analysis revealed that the anti-obesity effect of ghrelinR inverse agonists depends on their brain concentrations.
