39055-47-5

Basic information

• Product Name: 1,4-Naphthalenediol, 2-bromo-3-methyl-
• Synonyms: 1,4-Naphthalenediol,2-bromo-3-methyl;2-Brom-3-methyl-naphthalin-1,4-diol;2-bromo-3-methyl-naphthalene-1,4-diol;3-Brom-1.4-dihydroxy-2-methyl-naphthalin;2-bromo-3-methylnaphthohydroquinone
• CAS NO: 39055-47-5
• Molecular Formula: C11H9BrO2
• Molecular Weight: 253.095
• Mol File: 39055-47-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4-Naphthalenediol, 2-bromo-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Naphthalenediol, 2-bromo-3-methyl-(39055-47-5)
• EPA Substance Registry System: 1,4-Naphthalenediol, 2-bromo-3-methyl-(39055-47-5)

Safety Data

• Hazardous Substances Data: 39055-47-5(Hazardous Substances Data)

Upstream product

• 58-27-5 menadione 
• 861047-23-6 2,3-dibromo-2-methyl-2,3-dihydro-[1,4]naphthoquinone 
• 861331-93-3 4-chloro-2-methylnaphthalen-1-ol 
• 3129-39-3 2-bromo-3-methyl-[1,4]naphthoquinone 
• 17735-17-0 2,3,4,4-tetrachloro-2-methyl-3,4-dihydro-2H-naphthalen-1-one 

Downstream Products

• 827347-03-5 2-(3-methyl-1,4-dioxo-1,4-dihydro-2-naphthalenyl)benzaldehyde 
• 827347-02-4 2-(1,4-dimethoxy-3-methyl-2-naphthyl)benzaldehyde 
• 2498-66-0 benz[a]anthracene-7,12-dione 
• 16354-53-3 7,12-dimethoxybenzo[a]anthracene 
• 84-80-0 vitamin K₁ 
• 481-85-6 2-methyl-1,4-naphthohydroquinone 
• 139553-45-0 2-Methyl-3-methylsulfanyl-naphthalene-1,4-diol 
• 53772-33-1 2-bromo-3-methyl-1,4-dimethoxynaphthalene 

Relevant articles and documents

Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation

Malaria is a tropical parasitic disease threatening populations in tropical and sub-tropical areas. Resistance to antimalarial drugs has spread all over the world in the past 50 years, thus new drugs are urgently needed. Plasmodione (benzylmenadione series) has been identified as a potent antimalarial early lead drug, acting through a redox bioactivation on asexual and young sexual blood stages. To investigate its metabolism, a series of plasmodione-based tools, including a fully 13C-labelled lead drug and putative metabolites, have been designed and synthesized for drug metabolism investigation. Furthermore, with the help of UHPLC-MS/MS, two of the drug metabolites have been identified from urine of drug-treated mice.