39082-07-0

Basic information

• Product Name: 2-Selenophenecarbonylchloride(6CI,9CI)
• Synonyms: 2-Selenophenecarbonylchloride(6CI,9CI)
• CAS NO: 39082-07-0
• Molecular Formula: C₅H₃ClOSe
• Molecular Weight: 193.48972
• Product Categories: ACIDHALIDE
• Mol File: 39082-07-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Selenophenecarbonylchloride(6CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Selenophenecarbonylchloride(6CI,9CI)(39082-07-0)
• EPA Substance Registry System: 2-Selenophenecarbonylchloride(6CI,9CI)(39082-07-0)

Safety Data

• Hazardous Substances Data: 39082-07-0(Hazardous Substances Data)

Upstream product

• 15429-03-5 2-acetylselenophene 
• 25109-26-6 selenophene-2-carbaldehyde 
• 22968-45-2 Selenophene-2-carboxylic acid 

Downstream Products

• 55685-51-3 2-(N,N-Dimethylcarboxamido)-selenophen 
• 1032315-50-6 dibenzyl 2-(2'-selenophenyl)-6,7-methylenedioxyquinolin-4-yl-phosphate 
• 1350903-36-4 N-(2-acetyl-3,4-dimethoxyphenyl)selenophene-2-carboxamide 
• 1350903-37-5 N-(2-acetyl-4-methoxyphenyl)selenophene-2-carboxamide 
• 1346457-01-9 succinic acid mono-[5-(1-benzyl-selenolo[3,2-c]pyrazol-3-yl)furan-2-yl]methyl ester 
• 1346456-97-0 C₁₈H₁₆N₂O₃Se 
• 1346456-69-6 5-methoxycarbonyl-2-furyl 2-selenophenyl phenylhydrazone 
• 1223581-05-2 1-benzyl-3-(5-hydroxycarbonyl-2-furyl)selenolo[3,2-c]pyrazole 
• 1115951-96-6 1-benzyl-3-(5-hydroxymethyl-2-furyl)selenolo[3,2-c]pyrazole 
• 1223580-94-6 1-benzyl-3-(5-methoxycarbonyl-2-furyl)selenolo[3,2-c]pyrazole 
• 1223581-04-1 1-phenyl-3-(5-hydroxycarbonyl-2-furyl)selenolo[3,2-c]pyrazole 
• 1223580-99-1 1-phenyl-3-(5-hydroxymethyl-2-furyl)selenolo[3,2-c]pyrazole 
• 1223580-93-5 1-phenyl-3-(5-methoxycarbonyl-2-furyl)selenolo[3,2-c]pyrazole 

Relevant articles and documents

Selenolopyrazole derivatives and use thereof as anticancer agents

The present invention synthesizes a series of selenolo[3,2-c]pyrazole and selenolo[2,3-c]pyrazole derivatives, and discovers their anticancer activity.

Synthesis of 1-benzyl-3-(5-hydroxymethyl-2-furyl)selenolo[3,2-c]pyrazole derivatives as new anticancer agents

As part of our continuing search for potential anticancer drug candidates among YC-1 analogs, 1, 3-disubstituted selenolo[3,2-c]pyrazole derivatives were synthesized and evaluated for their cytotoxicity against NCI-H226 non-small cell lung cancer and A-498 renal cancer cell lines. Significant cytotoxicity was observed in 3-(5-hydroxymethyl-2-furyl) derivatives (2, 33, 36 and 37). Among them, compound 2 was found to have the most potent activity. The mode of action of compound 2 seems to differ from those of the 175 anticancer agents listed in NCI's standard database and resembles that of YC-1. Thus, we recommend that compound 2 should be developed further as new drug candidate for treatment of non-small cell lung cancer and renal cancer.