391-92-4 Usage
Description
METHYL 5-FLUORO-2-HYDROXYBENZOATE is a pale yellow low melting solid that serves as a crucial intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows it to be a versatile building block in the development of new drugs and other chemical products.
Uses
Used in Pharmaceutical Industry:
METHYL 5-FLUORO-2-HYDROXYBENZOATE is used as a pharmaceutical intermediate for the development of new drugs. Its chemical properties make it a valuable component in the synthesis of various medications, contributing to the advancement of medical treatments.
Used in Organic Synthesis:
In the field of organic chemistry, METHYL 5-FLUORO-2-HYDROXYBENZOATE is utilized as an intermediate in the synthesis of a wide range of organic compounds. Its unique structure allows for the creation of diverse chemical products, expanding the possibilities for research and development in this field.
Used in Laboratory Research:
METHYL 5-FLUORO-2-HYDROXYBENZOATE is also employed in laboratory settings for research purposes. Its properties make it an ideal candidate for studying various chemical reactions and processes, furthering our understanding of organic chemistry and its applications in various industries.
Synthesis
Methyl 5-fluoro-2-hydroxybenzoate is synthesized by esterification of 5-fluorosalicylic acid with methanol.
Check Digit Verification of cas no
The CAS Registry Mumber 391-92-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 391-92:
(5*3)+(4*9)+(3*1)+(2*9)+(1*2)=74
74 % 10 = 4
So 391-92-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FO3/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4,10H,1H3
391-92-4Relevant articles and documents
Rhodium(III)-Catalyzed Oxidative Intramolecular 1,1-Oxyamination of Alkenes with Protected Amino Acids to Produce Oxazoloisoindole-2,5-diones
Takahashi, Hiroto,Nagashima, Yuki,Tanaka, Ken
supporting information, p. 1891 - 1895 (2021/04/05)
It has been established that an electron-deficient bis(ethoxycarbonyl)-substituted cyclopentadienyl (CpE) rhodium(III) complex catalyzes the oxidative intramolecular 1,1-oxyamination of alkenes with N-benzoyl amino acids to produce oxazoloisoindole-2,5-diones. Experimental and theoretical mechanistic studies revealed that this oxidative 1,1-oxyamination proceeds via not the aza-Wacker reaction but the formation of a rhoda(III)oxazolidine initiated by the carboxylic acid-directed N?H bond cleavage.
MODIFIED COMPOUND OF ANDROGRAPHOLIDE
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Paragraph 0184-0186, (2019/01/04)
The present disclosure discloses a modified compound of andrographolide, and particularly discloses a compound shown in formula (I) and (II) or a pharmaceutically acceptable salt thereof.
NEW ANTIBACTERIAL COMPOUNDS
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Page/Page column 46, (2018/01/19)
The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
