39142-92-2

Basic information

• Product Name: 1H-Isoindol-1-one, 2,3-dihydro-2,3-bis(phenylmethyl)-
• CAS NO: 39142-92-2
• Molecular Formula: C22H19NO
• Molecular Weight: 313.399
• Mol File: 39142-92-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Isoindol-1-one, 2,3-dihydro-2,3-bis(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-1-one, 2,3-dihydro-2,3-bis(phenylmethyl)-(39142-92-2)
• EPA Substance Registry System: 1H-Isoindol-1-one, 2,3-dihydro-2,3-bis(phenylmethyl)-(39142-92-2)

Safety Data

• Hazardous Substances Data: 39142-92-2(Hazardous Substances Data)

Upstream product

• 293744-55-5 N-benzyl-2-(2'-phenylethynyl)benzamide 
• 60901-21-5 o-styrylbenzoic acid 
• 100-42-5 styrene 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 907174-66-7 C₁₅H₁₁ClO 
• 100-46-9 benzylamine 
• 118-92-3 anthranilic acid 
• 73178-23-1 N-benzyl-2-iodobenzamide 
• 609-67-6 2-Iodobenzoyl chloride 
• 88-67-5 2-Iodobenzoic acid 
• 566151-93-7 2,3-dibenzyl-3-phenylsulfanyl-2,3-dihydro-isoindol-1-one 
• 19793-96-5 (Z)-2-benzyl-3-benzylidene-2,3-dihydro-1H-isoindolin-1-one 
• 86769-98-4 (E)-N-benzyl-2-styrylbenzamide 
• 66050-02-0 N,9-dibenzyl-8-azabicyclo<4.3.0>nona-1(6),3-dien-7-one 

Relevant articles and documents

Intramolecular Hydroamidation of ortho-Vinyl Benzamides Promoted by Potassium tert-Butoxide/N,N-Dimethylformamide

An intramolecular hydroamidation of ortho-vinyl benzamides had been developed. The reaction was promoted efficiently by potassium tert-butoxide and N,N-dimethylformamide without the need for strong oxidants or transition-metal catalysts. A series of dihyd

A new entry for the preparation of substituted aromatic carbonyl compounds mediated by Samarium(II) iodide

A new route to substituted aromatic lactones and lactams via SMI2-promoted desulfurization is described. Direct replacement of the phenylthio substituent by hydroxyalkylated groups featuring the novel accessible process for the construction of continuous quaternary carbon centers could be accomplished when the same type of reactions was undertaken with carbonyl compounds in the presence of SmI2.

The Reduction of Tertiary N-Styrylenamides

Magnesium and methanol reduction of N,9-dibenzyl-8-azabicyclonon-1(6)-en-7-one (6) gave all four racemates of N,9-dibenzyl-8-azabicyclononan-7-one (1)-(4), with a 13:6 ratio of cis-fused to trans-fused products.Selective reduction of N,9-dibenzyl-8-azabicyclonon-1(6),3-dien-7-one (5) gave almost exclusively the two cis-fused racemates of N,9-dibenzyl-8-azabicyclonon-3-en-7-one (9) and (10).Magnesium and methanol did not reduce (E)-N-benzyl-9-benzylidene-cis-bicyclononan-7-one (7) and (E)-N-benzyl-N-(1-methyl-2-phenylvinyl)-acetamide (16a), but did reduce (E)-N-benzyl-N-styrylacetamide (16b) and (E)- and (Z)-N-styrylpyrrolidin-2-one (13) and (14); incomplete reduction of (Z)-N-benzyl-N-(1-methyl-2-phenylvinyl)-acetamide (15a) and (Z)-N-benzyl-N-styrylacetamide (15b) was observed.Reduction does not occur when the styryl phenyl group is twisted out of conjugation.Sodium and liquid ammonia reduction of (E)-N-benzyl-9-benzylidene-cis-8-azabicyclononan-7-one (7) gave (1RS,6SR,9RS)-9-benzyl-8-azabicyclononan-7-one and N-benzyl-2-(2-phenylethyl)cyclohexane-1-carboxamide (20).A similar cleavage of the β-styryl-nitrogen bond was observed in the reduction of (Z)-N-benzyl-N-(1-methyl-2-phenylvinyl)acetamide (15a), but not with (E)-N-styrylpyrrolidin-2-one (13).Several tertiary N-styrylenamides were not reduced by sodium cyanoborohydride in acetic acid but N-benzyl-9-benzylidene-cis-8-azabicyclonon-3-en-7-one (8) and N-benzyl-9-benzylidene-cis-8-azabicyclononan-7-one (7) gave (1RS,6SR,9RS)-N,9-dibenzyl-8-azabicyclonon-3-en-7-one (9) and (1RS,6SR,9RS)-N,9-dibenzyl-8-azabicyclononan-7-one (2) respectively.