39180-42-2

Basic information

• Product Name: 9H-FLUORENE-2-CARBONYL CHLORIDE,9-OXO
• Synonyms: 9H-FLUORENE-2-CARBONYL CHLORIDE,9-OXO
• CAS NO: 39180-42-2
• Molecular Formula: C₁₄H₇ClO₂
• Molecular Weight: 0
• Mol File: 39180-42-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 9H-FLUORENE-2-CARBONYL CHLORIDE,9-OXO(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-FLUORENE-2-CARBONYL CHLORIDE,9-OXO(39180-42-2)
• EPA Substance Registry System: 9H-FLUORENE-2-CARBONYL CHLORIDE,9-OXO(39180-42-2)

Safety Data

• Hazardous Substances Data: 39180-42-2(Hazardous Substances Data)

Upstream product

• 781-73-7 1-(9H-fluoren-2-yl)ethanone 
• 86-73-7 9H-fluorene 
• 784-50-9 fluorenone-2-carboxylic acid 

Relevant articles and documents

General C-H Arylation Strategy for the Synthesis of Tunable Visible Light-Emitting Benzo[a]imidazo[2,1,5-c,d]indolizine Fluorophores

Herein we report the discovery of the benzo[a]imidazo[2,1,5-c,d]indolizine motif displaying tunable emission covering most of the visible spectrum. The polycyclic core is obtained from readily available amides via a chemoselective process involving Tf2O-mediated amide cyclodehydration, followed by intramolecular C-H arylation. Additionally, these fluorescent heterocycles are easily functionalized using electrophilic reagents, enabling divergent access to varied substitution. The effects of said substitution on the compounds' photophysical properties were rationalized by density functional theory calculations. For some compounds, emission wavelengths are directly correlated to the substituent's Hammett constants. Easily introduced nonconjugated reactive functional groups allow the labeling of biomolecules without modification of emissive properties. This work provides a straightforward platform for the synthesis of new moderately bright fluorescent dyes remarkable for their chemical stability, predictability, and unusually high excitation-emission differential.

Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849

A strategy of systematically targeting more rigid analogues of the known MCH R1 receptor antagonist, SB-568849, serendipitously uncovered a binding mode accessible to N-aryl-phthalimide ligands. Optimisation to improve the stability of this compound class led to the discovery of novel N-aryl-quinazolinones, benzotriazinones and thienopyrimidinones as selective ligands with good affinity for human melanin-concentrating hormone receptor 1.

Bichromophoric perylene derivatives: Energy transfer from non-fluorescent chromophores

The energy of excitation at non-fluorescent chromophores such as fluorenone and anthraquinone has been trapped by a fast energy transfer to the highly fluorescent perylene bisimides. To this end, anthraquinone, fluorenone and anthracene derivatives have been linked to the perylene bisimides by non-conjugating spacers and fluorescence quantum yield of such assemblies have been determined as a function of the wavelengths of excitation. Energy transfer in such assemblies is strongly influenced by the orientation of the two chromophores. This is of interest for the construction of fluorescence switches.