39190-98-2

Basic information

• Product Name: N-(3-chlorobenzyl)-N-propylamine
• Synonyms: N-(3-chlorobenzyl)-N-propylamine;(3-CHLOROBENZYL)PROPYLAMINE;AKOS LT-1098X1829;N-(3-CHLOROPHENYLMETHYL)PROPYLAMINE;UKRORGSYN-BB BBV-068207;(3-chlorobenzyl)propylamine(SALTDATA: HCl);N-(3-Chlorobenzyl)propan-1-aMine;[(3-chlorophenyl)methyl](propyl)amine
• CAS NO: 39190-98-2
• Molecular Formula: C₁₀H₁₄ClN
• Molecular Weight: 183.6779
• Mol File: 39190-98-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 245.8 °C at 760 mmHg
• Flash Point: 102.4 °C
• Appearance: /
• Density: 1.043 g/cm³
• Vapor Pressure: 0.0282mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: N-(3-chlorobenzyl)-N-propylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chlorobenzyl)-N-propylamine(39190-98-2)
• EPA Substance Registry System: N-(3-chlorobenzyl)-N-propylamine(39190-98-2)

Safety Data

• Hazardous Substances Data: 39190-98-2(Hazardous Substances Data)

Usage

Uses

(m-Chlorobenzyl)propylamine acts as a reagent in the preparation of novel dimethoxy-N2-(substituted benzyl)-N2-propylquinazoline diamine derivatives as anxiolytic and antidepressant agents

InChI:InChI=1/C10H14ClN/c1-2-6-12-8-9-4-3-5-10(11)7-9/h3-5,7,12H,2,6,8H2,1H3

Upstream product

• 107-10-8 propylamine 
• 587-04-2 m-Chlorobenzaldehyde 
• 1032080-61-7 [1-(3-Chloro-phenyl)-meth-(E)-ylidene]-propyl-amine 

Relevant articles and documents

Synthesis and biological activity of some novel substituted quinazoline derivatives

A new series of 4-N-(substituted benzyl)-2-phenyl-N-propylquinazolines were synthesized. The structures of the synthesized compounds were confirmed by IR, 1H NMR, 13C NMR and mass spectral analysis. All the synthesized compounds were screened for their analgesic and anti-inflammatory activity. Among the synthesized compounds 5c, 5h and 5o exhibited significant analgesic activity at 60 and 90 minutes reading, while compounds 5g, 5k and 5l exhibited significant anti-inflammatory activity at 3rd and 4th hr reading.

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.