391904-95-3

Basic information

• Product Name: 5-[1-[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-phenyl]-meth-(Z)-ylidene]-thiazolidine-2,4-dione
• Synonyms: 5-[1-[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-phenyl]-meth-(Z)-ylidene]-thiazolidine-2,4-dione
• CAS NO: 391904-95-3
• Molecular Weight: 346.407
• Mol File: 391904-95-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[1-[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-phenyl]-meth-(Z)-ylidene]-thiazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[1-[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-phenyl]-meth-(Z)-ylidene]-thiazolidine-2,4-dione(391904-95-3)
• EPA Substance Registry System: 5-[1-[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-phenyl]-meth-(Z)-ylidene]-thiazolidine-2,4-dione(391904-95-3)

Safety Data

• Hazardous Substances Data: 391904-95-3(Hazardous Substances Data)

Upstream product

• 2295-31-0 thiazoline-2,4-dione 
• 79421-40-2 4-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)benzaldehyde 

Downstream Products

• 344604-91-7 5-[4-(4-oxopiperidin-1-yl)benzyl]thiazolidine-2,4-dione 
• 391904-97-5 5-[4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-benzyl]-thiazolidine-2,4-dione 

Relevant articles and documents

2,4-Thiazolidinediones as potent and selective human β3 agonists

Methylsulfonamide substituted 2,4-thiazolidinedione 22c is a potent (EC50 = 0.01 μM, IA = 1.19) and selective (more than 110-fold over β1 and β2 agonist activity) β3 agonist. This compound has also been proven to be active and selective in an in vivo mode.