39251-91-7

Basic information

• Product Name: 2-Furancarboxylic acid, cyclohexyl ester
• CAS NO: 39251-91-7
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 39251-91-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Furancarboxylic acid, cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxylic acid, cyclohexyl ester(39251-91-7)
• EPA Substance Registry System: 2-Furancarboxylic acid, cyclohexyl ester(39251-91-7)

Safety Data

• Hazardous Substances Data: 39251-91-7(Hazardous Substances Data)

Usage

Description

2-Furancarboxylic acid, cyclohexyl ester is a colorless liquid chemical compound with the molecular formula C12H14O3. It is an ester formed by the condensation of cyclohexanol and 2-furancarboxylic acid, characterized by its fruity odor.

Uses

Used in Food Industry:
2-Furancarboxylic acid, cyclohexyl ester is used as a flavoring agent for its distinctive fruity scent, enhancing the taste and aroma of various food products.
Used in Pharmaceutical Industry:
2-Furancarboxylic acid, cyclohexyl ester is utilized as a chemical intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Organic Compounds Synthesis:
2-Furancarboxylic acid, cyclohexyl ester serves as a key intermediate in the synthesis of other organic compounds, playing a crucial role in the production of various chemical products.
Safety Note:
Although considered a low-toxicity substance, 2-Furancarboxylic acid, cyclohexyl ester should be handled with care to avoid potential skin and eye irritation.

Upstream product

• 527-69-5 2-furancarbonyl chloride 
• 108-93-0 cyclohexanol 

Downstream Products

• 4282-32-0 furan-2,5-dicarboxylic acid dimethyl ester 

Relevant articles and documents

Synthesis of [2,2’]Bifuranyl-5,5’-dicarboxylic Acid Esters via Reductive Homocoupling of 5-Bromofuran-2-carboxylates Using Alcohols as Reductants?

Herein, we describe an environmentally benign and cost-effective protocol for the synthesis of valuable bifuranyl dicarboxylates, starting with α-bromination of readily accessible furan-2-carboxylates by LiBr and K2S2O8. Furthermore, the bromination intermediate product 5-bromofuran-2-carboxylates were then conducted in a palladium-catalyzed reductive homocoupling reactions in the presence of alcohols to afford bifuranyl dicarboxylates. One of the final products in this protocol, [2,2’]bifuran-5,5’-dicarboxylic acid esters, are essential monomers of poly(ethylene bifuranoate), which can be served as an green and versatile alternative polymer for traditional poly(ethylene terephthalate) that is currently common in technical plastics.

Highly Active Manganese-Mediated Acylation of Alcohols with Acid Chlorides or Anhydrides

To explore further the practical uses of highly active manganese (Mn?), a variety of alcohols were treated with Mn?, and the resulting complexes were coupled with acid chlorides and/or acetic anhydride in the absence of any extra catalyst. The subsequent reactions took place smoothly under mild conditions, providing the corresponding O-acylation products in good to excellent isolated yields.