39262-14-1 Usage
Description
(20S)-20-(β-D-Glucopyranosyloxy)dammara-24-ene-3β,12β-diol is a primary reference substance with assigned absolute purity, which takes into account chromatographic purity, water, residual solvents, and inorganic impurities. The exact purity value can be found on the certificate.
Uses
Used in Pharmaceutical Industry:
(20S)-20-(β-D-Glucopyranosyloxy)dammara-24-ene-3β,12β-diol is used as a pharmaceutical compound for its potential therapeutic applications. It has been reported to exhibit anti-cancer properties, making it a candidate for the development of new cancer treatments.
Used in Cosmetic Industry:
In the cosmetic industry, (20S)-20-(β-D-Glucopyranosyloxy)dammara-24-ene-3β,12β-diol is used as an active ingredient for its anti-wrinkle effects, contributing to the development of anti-aging skincare products.
Used in Research Applications:
(20S)-20-(β-D-Glucopyranosyloxy)dammara-24-ene-3β,12β-diol is also utilized in research settings as a reference substance for studying its biological activities and potential interactions with various cellular pathways, which can lead to the discovery of new therapeutic targets and applications.
Properties
Ginsenoside CK is a white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ginseng rhizome, Gynostemma pentaphyllum.
Pharmacological action
Ginsenoside CK is the main metabolite of protopanaxadiol saponins in human intestinal tract. Studies have shown that the pharmacological activities of ginsenosides are mainly mediated through its metabolic component CK, and CK has a variety of pharmacological activities, such as anti-inflammatory, anti-tumor, anti-allergic, anti-diabetic, hepatoprotective, neuroprotective, and cardiovascular protection.
Check Digit Verification of cas no
The CAS Registry Mumber 39262-14-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,6 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 39262-14:
(7*3)+(6*9)+(5*2)+(4*6)+(3*2)+(2*1)+(1*4)=121
121 % 10 = 1
So 39262-14-1 is a valid CAS Registry Number.
InChI:InChI=1/C36H62O8/c1-20(2)10-9-14-36(8,44-31-30(42)29(41)28(40)23(19-37)43-31)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(39)32(3,4)24(33)12-17-34(25,35)6/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1
39262-14-1Relevant articles and documents
Rational design of a β-glycosidase with high regiospecificity for triterpenoid tailoring
Park, Sang Jin,Choi, Jung Min,Kyeong, Hyun-Ho,Kim, Song-Gun,Kim, Hak-Sung
, p. 854 - 860 (2015)
Triterpenoids with desired glycosylation patterns have attracted considerable attention as potential therapeutics for inflammatory diseases and various types of cancer. Sugar-hydrolyzing enzymes with high substrate specificity would be far more efficient than other methods for the synthesis of such specialty triterpenoids, but they are yet to be developed. Here we present a strategy to rationally design a β-glycosidase with high regiospecificity for triterpenoids. A β-glycosidase with broad substrate specificity was isolated, and its crystal structure was determined at 2.0 ? resolution. Based on the product profiles and substrate docking simulations, we modeled the substrate binding modes of the enzyme. From the model, the substrate binding cleft of the enzyme was redesigned in a manner that preferentially hydrolyzes glycans at specific glycosylation sites of triterpenoids. The designed mutants were shown to produce a variety of specialty triterpenoids with high purity.
