393164-93-7

Basic information

• Product Name: methyl 2-diazo-2-(3,4-dichlorophenyl)acetate
• Synonyms: methyl 2-diazo-2-(3,4-dichlorophenyl)acetate
• CAS NO: 393164-93-7
• Molecular Weight: 245.065
• Mol File: 393164-93-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: methyl 2-diazo-2-(3,4-dichlorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-diazo-2-(3,4-dichlorophenyl)acetate(393164-93-7)
• EPA Substance Registry System: methyl 2-diazo-2-(3,4-dichlorophenyl)acetate(393164-93-7)

Safety Data

• Hazardous Substances Data: 393164-93-7(Hazardous Substances Data)

Upstream product

• 941-55-9 4-toluenesulfonyl azide 
• 6725-44-6 methyl 2-(3,4-dichlorophenyl)acetate 
• 5807-30-7 3,4-dichlorophenyl acetic acid 

Downstream Products

• 1403365-79-6 (E)-methyl 1-(3,4-dichlorophenyl)-2-styrylcyclopropanecarboxylate 
• 1011458-49-3 ethyl 2-[(4,5-dichloro-2-methoxycarbonylmethyl)phenyl]-2-(phenylthio)acetate 
• 1011458-63-1 methyl 2-{4,5-dichloro-2-[cyano(phenylthio)methyl]phenyl}acetate 
• 909487-62-3 methyl 3-amino-(2S)-(3,4-dichlorophenyl)propionate 
• 1011528-31-6 (R)-(-)-methyl 2-(3,4-dichlorophenyl)-2-hydroxyacetate 
• 393164-98-2 rac-(cyclohex-2-enyloxy)-(3,4-dichloro-phenyl)-acetic acid methyl ester 
• 939985-34-9 2-(3,4-dichlorophenyl)-2-(phenylthio)penta-3,4-dienal 
• 64471-84-7 (3,4-dichloro-phenyl)-oxo-acetic acid methyl ester 
• 86939-10-8 indatraline 
• 86939-10-8 indatraline 

Relevant articles and documents

Divergent Synthesis of Aziridine and Imidazolidine Frameworks under Blue LED Irradiation

We develop a visible light-promoted divergent cycloaddition of α-diazo esters with hexahydro-1,3,5-triazines, leading to a series of aziridine and imidazolidine frameworks in average good yield, by simply changing the reaction media used. It is noteworthy that the reaction occurs under sole visible light irradiation without the need for exogenous photoredox catalysts. More significantly, a reasonable reaction mechanism was proposed on the basis of the control experiments and density functional theory calculation results.

Visible Light-Promoted Sulfoxonium Ylides Synthesis from Aryl Diazoacetates and Sulfoxides

A visible light-promoted reaction of donor/acceptor diazoalkanes with sulfoxides towards the synthesis of synthetically useful sulfoxonium ylides was reported. The reaction occurred under sole visible light irradiation without the need of any transition-metals or additives, affording the corresponding sulfoxonium ylides in moderate to good yields. The success of late-stage modification of natural isolates or drug candidates, scale-up reaction and transformation of sulfoxonium ylides to other useful molecules further rendered the approach valuable.

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se