395065-67-5

Basic information

• Product Name: methyl (5S)-5-(3-fluorophenyl)-3-oxo-6-heptenoate
• Synonyms: methyl (5S)-5-(3-fluorophenyl)-3-oxo-6-heptenoate
• CAS NO: 395065-67-5
• Molecular Weight: 250.27
• Mol File: 395065-67-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (5S)-5-(3-fluorophenyl)-3-oxo-6-heptenoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (5S)-5-(3-fluorophenyl)-3-oxo-6-heptenoate(395065-67-5)
• EPA Substance Registry System: methyl (5S)-5-(3-fluorophenyl)-3-oxo-6-heptenoate(395065-67-5)

Safety Data

• Hazardous Substances Data: 395065-67-5(Hazardous Substances Data)

Upstream product

• 26905-44-2 3-(3-fluorophenyl)-2-propen-1-ol 
• 456-48-4 3-Fluorobenzaldehyde 
• 1026720-66-0 2-[(R)-1-(3-Fluoro-phenyl)-allyl]-malonic acid 
• 335314-64-2 1-(3-fluorophenyl)-prop-2-enyl methyl carbonate 
• 38330-80-2 monomethyl monopotassium malonate 
• 395065-66-4 (3S)-3-(3-fluorophenyl)-4-pentenoic acid 

Downstream Products

• 313502-76-0 (+)-trans-3-hydroxymethyl-4-(3-fluorophenyl)cyclopentan-1-one 
• 121-61-9 p-acetylaminobenzenesulfonamide 
• 395065-68-6 methyl (5S)-2-diazo-5-(3-fluorophenyl)3-oxo-6-heptenoate 

Relevant articles and documents

Iridium-catalyzed direct asymmetric vinylogous allylic alkylation

The catalytic asymmetric vinylogous allylic alkylation of α,β-unsaturated lactones (including coumarins) was achieved with excellent regio- and enantioselectivity. Transformations of the product were carried out by means of the versatile terminal olefin and lactone moieties. The synthetic application of the present methodology was showcased by the asymmetric synthesis of an advanced synthetic Merck intermediate toward a new drug candidate.