39545-99-8Relevant articles and documents
A pyridylsilyl group expands the scope of catalytic intermolecular Pauson-Khand reactions
Itami, Kenichiro,Mitsudo, Koichi,Yoshida, Jun-Ichi
, p. 3481 - 3484 (2002)
Now even unstrained alkenes can be used in catalytic intermolecular Pauson-Khand reactions [Eq. (a)]. This is made possible by the use of the directing group dimethyl(2-pyridyl)silyl, which can be easily removed at the end of the reaction. Furthermore, one observes completely regioselective incorporation of substituents at the 4- and 5-positions of the 2-cyclopentenone structure.
Aqueous chemoenzymatic one-pot enantioselective synthesis of tertiary α-aryl cycloketonesviaPd-catalyzed C-C formation and enzymatic C=C asymmetric hydrogenation
Luan, Pengqian,Liu, Yunting,Li, Yongxing,Chen, Ran,Huang, Chen,Gao, Jing,Hollmann, Frank,Jiang, Yanjun
, p. 1960 - 1964 (2021/03/26)
An aqueous chemoenzymatic cascade reaction combining Pd-catalyzed C-C formation and enzymatic C=C asymmetric hydrogenation (AH) was developed for enantioselective synthesis of tertiary α-aryl cycloketones in good yields and excellent enantioselectivities. The stereopreference of the enzyme in AH of α-aryl cyclohexenones was studied. An enantiocomplementary enzyme was obtained by site-directed mutation.
METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID
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Paragraph 0207; 0211; 0212; 0213, (2018/03/25)
The present invention relates to compounds of formula (I): in which R1 is a hydrogen atom, a phenyl radical, or a straight or branched, saturated or unsaturated hydrocarbon radical having 1 to 8 carbon atoms.