3958-57-4 Usage
Description
3-Nitrobenzyl bromide is a pale yellow crystalline solid that is commonly utilized in various chemical reactions and processes due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3-Nitrobenzyl bromide is used as a synthetic intermediate for the production of various pharmaceutical compounds, particularly in the synthesis of 1,4-disubstituted imidazoles. These imidazoles are important in the development of drugs targeting a wide range of medical conditions.
Used in Chemical Synthesis:
3-Nitrobenzyl bromide serves as a valuable building block in the synthesis of various organic compounds, including those with potential applications in the fields of materials science, agrochemicals, and specialty chemicals. Its reactivity and functional group compatibility make it a versatile component in the creation of complex molecular structures.
Used in Research and Development:
In academic and industrial research settings, 3-Nitrobenzyl bromide is employed as a key reactant in the development of new chemical methodologies and the exploration of novel reaction pathways. Its unique properties allow chemists to investigate a wide array of chemical transformations and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 3958-57-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,5 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3958-57:
(6*3)+(5*9)+(4*5)+(3*8)+(2*5)+(1*7)=124
124 % 10 = 4
So 3958-57-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrNO2/c8-5-6-2-1-3-7(4-6)9(10)11/h1-4H,5H2
3958-57-4Relevant articles and documents
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Bowden,K.,Cook,R.S.
, p. 1529 - 1533 (1968)
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(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER
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Paragraph 00339, (2020/07/15)
The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.
Reversible photoresponsive activity of a carbonic anhydrase mimic
Saha, Monochura,Bandyopadhyay, Subhajit
supporting information, p. 3294 - 3297 (2019/04/09)
The carbonic anhydrase (CA) enzyme reversibly transforms carbon dioxide and water to a carbonate ion and a proton. Photoresponsive enzyme mimics, where the CA-activity can be turned on and off reversibly with light, have not been reported so far. We have designed an active site mimic that offers reversible control of the catalytic activity using light. Moreover, in the presence of a cationic polymer, we have demonstrated that the CA-activity was further enhanced by stabilizing the transition state with the cis-form of the enzyme mimic which can catalyze the hydration of gaseous CO2.