396133-32-7

Basic information

• Product Name: Piperazine, 1,2,2-trimethyl- (9CI)
• Synonyms: Piperazine, 1,2,2-trimethyl- (9CI);1,2,2-trimethylpiperazine hydrochloride;1,2,2-trimethylpiperazine(SALTDATA: 2HCl);1,2,2-triMethylpiperazine dihydrochloride (SALTDATA: 2HCl);1,2,2-Trimethylpiperazine;1,2,2-TrimethylpiperazineHCl;1,2,2-triMethylpiperazine dihydrochloride
• CAS NO: 396133-32-7
• Molecular Formula: C₇H₁₆N₂
• Molecular Weight: 128.21534
• Product Categories: PIPERAZINE;AMINETERTIARY
• Mol File: 396133-32-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 151.317 °C at 760 mmHg
• Flash Point: 38.12 °C
• Appearance: /
• Density: 0.844 g/cm³
• Vapor Pressure: 3.685mmHg at 25°C
• Refractive Index: 1.432
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: Piperazine, 1,2,2-trimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1,2,2-trimethyl- (9CI)(396133-32-7)
• EPA Substance Registry System: Piperazine, 1,2,2-trimethyl- (9CI)(396133-32-7)

Safety Data

• Hazardous Substances Data: 396133-32-7(Hazardous Substances Data)

Usage

General Description

Piperazine, 1,2,2-trimethyl- (9CI) is a chemical compound commonly used as an intermediate in the production of pharmaceuticals, particularly antihistamines and analgesics. It is classified as a heterocyclic amine and is also utilized in the synthesis of various organic compounds. This chemical is known for its strong odor and is considered to be a toxic substance if ingested or inhaled in large quantities. Additionally, it is important to handle and store piperazine, 1,2,2-trimethyl- (9CI) with caution to prevent any potential health hazards. Its molecular formula is C6H14N2.

InChI:InChI=1/C7H16N2/c1-7(2)6-8-4-5-9(7)3/h8H,4-6H2,1-3H3

Upstream product

• 22476-74-0 3,3-dimethyl-piperazin-2-one 
• 86290-99-5 3,3,4-trimethylpiperazin-2-one 

Downstream Products

• 1104381-76-1 1-methyl-6-{3-(trifluoromethyl)-4-[3-(3,3,4-trimethylpiperazin-1-yl)-propoxy]-phenyl}-1H-imidazo[4,5-c]pyridine-4-carbonitrile trifluoroacetate 

Relevant articles and documents

BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION

The present invention relates to certain bis-heteroaryl compounds, pharmaceutical compositions containing them, and methods of using them, including methods for preventing, reversing, slowing, or inhibiting protein aggregation, and methods of treating diseases that are associated with protein aggregation, including neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, Lewy body disease, Parkinson's disease with dementia, fronto- temporal dementia, Huntington's Disease, amyotrophic lateral sclerosis, and multiple system atrophy, and cancer including melanoma.

SUCCINATE AND MALONATE SALT OF TRANS-4-(IR,3S)-6-CHLORO-3-PHENYLINDAN-1-YL)-1,2,2-TRIMETHYLPIPERAZINE AND THE USE AS A MEDICAMENT

4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate or hadrogen malonat, pharmaceutical compositions containing these salts and the medical use thereof, including for the treatment of schizophrenia and other psychotic diso