39731-22-1Relevant articles and documents
Identification of Xanthones as Selective Killers of Cancer Cells Overexpressing the ABC Transporter MRP1
Genoux-Bastide, Estelle,Lorendeau, Doriane,Nicolle, Edwige,Yahiaoui, Samir,Magnard, Sandrine,DiPietro, Attilio,Baubichon-Cortay, Helene,Boumendjel, Ahcene
, p. 1478 - 1484 (2011)
Multidrug-resistance protein1 (MRP1) belongs to the ATP-binding cassette (ABC) transporter family. MRP1 mediates MDR (multidrug resistance) by causing drug efflux either by conjugation to glutathione (GSH) or by co-transport with free GSH (without covalen