39739-46-3

Basic information

• Product Name: methyl valerimidate hydrochloride
• Synonyms: PentaniMidic acid, Methyl ester, hydrochloride;Methyl valeriMidate hydrochlorid
• CAS NO: 39739-46-3
• Molecular Formula: C₆H₁₃NO*ClH
• Molecular Weight: 151.6345
• EINECS: 254-610-9
• Product Categories: Aliphatics;Miscellaneous Reagents
• Mol File: 39739-46-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 82-84?C
• Boiling Point: 114.4°Cat760mmHg
• Flash Point: 23°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 23.7mmHg at 25°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• CAS DataBase Reference: methyl valerimidate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: methyl valerimidate hydrochloride(39739-46-3)
• EPA Substance Registry System: methyl valerimidate hydrochloride(39739-46-3)

Safety Data

• Hazardous Substances Data: 39739-46-3(Hazardous Substances Data)

Usage

Description

Methyl valerimidate hydrochloride, with the CAS number 39739-46-3, is a white solid compound that is primarily utilized in the field of organic synthesis. Its chemical structure and properties make it a valuable component in the creation of various organic compounds.

Uses

Used in Organic Synthesis:
Methyl valerimidate hydrochloride is used as a synthetic building block for the development of new organic compounds. Its unique chemical properties allow it to be a versatile reagent in the synthesis of various organic molecules, contributing to the advancement of chemical research and the creation of novel materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl valerimidate hydrochloride is used as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Its role in the development of new medications is crucial, as it can be used to create molecules with specific therapeutic properties, potentially leading to the discovery of new treatments for various diseases.
Used in Chemical Research:
Methyl valerimidate hydrochloride is also employed in chemical research as a tool to study the properties and reactions of different organic compounds. Its use in research helps scientists gain a deeper understanding of organic chemistry and develop new methodologies for the synthesis of complex molecules.

InChI:InChI=1/C6H13NO.ClH/c1-3-4-5-6(7)8-2;/h7H,3-5H2,1-2H3;1H/b7-6-;

Upstream product

• 67-56-1 methanol 
• 110-59-8 pentanonitrile 

Downstream Products

• 18257-46-0 pentanamidine hydrochloride 
• 13820-09-2 trimethyl orthovalerate 
• 624-24-8 methyl valerate 
• 193140-43-1 (pentanimidoylamino)acetic acid 
• 905456-94-2 C₃₈H₃₆N₆ 
• 68283-19-2 2-butyl-5-hydroxymethyl-1H-imidazole 

Relevant articles and documents

A flexible Pinner preparation of orthoesters: The model case of trimethylorthobenzoate

In the absence of additional solvents, a novel procedure was implemented for the synthesis of trimethylorthoesters through the Pinner reaction. At 5 °C, the reaction of both aliphatic and aromatic nitriles (RCN; R = Et, Bu, Ph) with a moderate excess of MeOH and gaseous HCl gave the corresponding imidate hydrochlorides [RC(NH)OR′·HCl] in excellent yields (>90%). At 25-65 °C, the methanolysis of alkyl imidate salts provided trimethylortho-propionate and valerate, while only traces of trimethylorthobenzoate (TMOB) were observed. However, the aromatic hydrochloride could be readily converted into the hydrogenphosphate salt [PhC(NH) OR′·H3PO4] which, in turn, underwent a selective (>80%) reaction with MeOH to produce TMOB in a 62% isolated yield. This allowed for an unprecedented Pinner-type synthesis of TMOB starting from benzonitrile, rather than from the highly toxic trichloromethylbenzene. Overall, remarkable improvements in safety and process intensification were achieved.

PREPARATION AND UTILITY OF SUBSTITUTED PHENYLTETRAZOLES

Disclosed herein are substituted phenyltetrazoles of Formula I, processes of preparation thereof, pharmaceutical compositions thereof, and the methods of their use thereof.

FUNGICIDAL HETEROCYCLIC COMPOUNDS

A compound which can specifically or selectively expresses an antifungal activity with a broad spectrum, based on the functional mechanism of 1,6-β-glucan synthesis inhibition, is provided, and an antifungal agent which comprises such a compound, a salt thereof or a solvate thereof is provided. A compound represented by the following formula (I), a salt thereof or a solvate thereof.