39757-34-1

Basic information

• Product Name: METHYL 4-(4-FLUOROPHENYL)-2,4-DIOXOBUTANOATE
• Synonyms: F80114;Methyl 4-fluoro-a,g-dioxo-benzenebutanoate;Methyl 4-(4-fluorophenyl)-2,4-dioxobutanoate≥ 98% (HPLC);methyl 4-(4-fluorophenyl)-2,4-diketobutyrate
• CAS NO: 39757-34-1
• Molecular Formula: C₁₁H₉FO₄
• Molecular Weight: 0
• Mol File: 39757-34-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 348.7°C at 760 mmHg
• Flash Point: 159.2°C
• Appearance: /
• Density: 1.278g/cm³
• Vapor Pressure: 4.94E-05mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: METHYL 4-(4-FLUOROPHENYL)-2,4-DIOXOBUTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-(4-FLUOROPHENYL)-2,4-DIOXOBUTANOATE(39757-34-1)
• EPA Substance Registry System: METHYL 4-(4-FLUOROPHENYL)-2,4-DIOXOBUTANOATE(39757-34-1)

Safety Data

• Hazardous Substances Data: 39757-34-1(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow powder

InChI:InChI=1/C11H9FO4/c1-16-11(15)10(14)6-9(13)7-2-4-8(12)5-3-7/h2-5H,6H2,1H3

Upstream product

• 553-90-2 Dimethyl oxalate 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 887250-27-3 3-(4-fluorobenzoyl)-5-phenyl-1,2,4,5-tetrahydropyrrolo[1,2-a]quinoxaline-1,2,4-trione 
• 170571-29-6 1-[4-(aminosulfonyl)phenyl]-5-(4-fluorophenyl)-1H-pyrazole-3-carboxamide 
• 170570-81-7 5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)-1H-pyrazole-3-carboxylic acid 
• 1437792-15-8 N-(6-chlorobenzo[d]thiazol-2-yl)-7-(4-fluorophenyl)-2-phenylpyrazolo[1,5-a]pyrimidine-5-carboxamide 
• 1437792-24-9 N-(6-methoxybenzo[d]thiazol-2-yl)-7-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidine-5-carboxamide 
• 1437792-27-2 N-(6-methoxybenzo[d]thiazol-2-yl)-2-phenyl-7-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide 
• 1437792-30-7 N-(benzo[d]thiazol-2-yl)-2-phenyl-7-(3,4,5-trimethoxy phenyl)pyrazolo [1,5-a]pyrimidine-5-carboxamide 
• 1017082-08-4 2-phenyl-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid 
• 1437792-20-5 N-(6-fluorobenzo[d]thiazol-2-yl)-7-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidine-5-carboxamide 
• 1449245-06-0 methyl 7-(4-fluorophenyl)-2-phenylpyrazolo[1,5-a]pyrimidine-5-carboxylate 
• 870704-22-6 C₁₀H₇FN₂O₂ 

Relevant articles and documents

Development of 1,5-Diaryl-Pyrazole-3-Formate Analogs as Antifungal Pesticides and Their Application in Controlling Peanut Stem Rot Disease

Stem rot disease caused by Sclerotium rolfsii is one of the destructive diseases in peanut and poses a big risk to peanut production. Current fungicides in the market have not provided satisfactory control efficacy and thus called for novel fungicides with different structures as an alternative treatment strategy. Our previously developed phenylpyrazole compound 3c demonstrated modest inhibitory effect against S. rolfsii. The following structure modification identified an unreported compound 6, which bears a 3-chloropyridinyl moiety as the most prominent derivative with an IC50 of 12 μg/ml in potato dextrose agar (PDA) assay, higher than those of 0.8 and 1.8 μg/ml associated with thifluzamide and tebuconazole, respectively. However, compound 6 showed similar controlling effects to those of thifluzamide and tebuconazole in field study. This study underscores the potential of 1,5-diaryl-pyrazole-3-formate as an antifungal candidate for stem rot disease management.

Non-peptide-based new class of platelet aggregation inhibitors: Design, synthesis, bioevaluation, SAR, and in silico studies

A series of 2-oxo-2-phenylethylidene linked 2-oxo-benzo[1,4]oxazine analogues 17a–x and 18a–o, incorporated with a variety of electron-withdrawing as well as electron-donating groups at ring A and ring C, were synthesized under greener conditions in excel

CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME

The present disclosure provides, in part, cyclic sulfamide compounds, and pharmaceutical compositions thereof, useful as modulators of Hepatitis B (HBV) core protein, and methods of treating Hepatitis B (HBV) infection.