39788-41-5

Basic information

• Product Name: 2,3,5,6-tetrahydro-1H-benzo[d]azocin-4-one
• CAS NO: 39788-41-5
• Molecular Weight: 175.23
• Mol File: 39788-41-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3,5,6-tetrahydro-1H-benzo[d]azocin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6-tetrahydro-1H-benzo[d]azocin-4-one(39788-41-5)
• EPA Substance Registry System: 2,3,5,6-tetrahydro-1H-benzo[d]azocin-4-one(39788-41-5)

Safety Data

• Hazardous Substances Data: 39788-41-5(Hazardous Substances Data)

Upstream product

• 37949-03-4 5,6,8,9-tetrahydrobenzo[7]annulen-7-one 
• 83-33-0 inden-1-one 

Relevant articles and documents

Two-carbon ring expansion of 1-indanones via insertion of ethylene into carbon-carbon bonds

A rhodium-catalyzed direct insertion of ethylene into a relatively unstrained carbon-carbon bond in 1-indanones is reported, which provides a two-carbon ring expansion strategy for preparing seven-membered cyclic ketones. As many 1-indanones are commercially available and ethylene is inexpensive, this strategy simplifies synthesis of benzocycloheptenones that are valuable synthetic intermediates for bioactive compounds but challenging to prepare otherwise. In addition, the reaction is byproduct-free, redox neutral, and tolerant of a wide range of functional groups, which may have implications on unconventional strategic bond disconnections for preparing complex cyclic molecules.