39835-28-4

Basic information

• Product Name: 5-NITRO-1,2-BENZISOXAZOLE
• Synonyms: 5-NITRO-1,2-BENZISOXAZOLE;1,2-Benzisoxazole,5-nitro-(6CI,9CI);5-Nitrobenzisoxazole;5-Nitroindoxazene;5-Nitro-1,2-benzoxazole;5-nitrobenzo[d]isoxazole
• CAS NO: 39835-28-4
• Molecular Formula: C₇H₄N₂O₃
• Molecular Weight: 164.12
• Product Categories: OXAZOLE
• Mol File: 39835-28-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 126-127 °C(Solv: ethanol (64-17-5))
• Boiling Point: 321.7°Cat760mmHg
• Flash Point: 148.4°C
• Appearance: /
• Density: 1.473g/cm³
• Vapor Pressure: 0.00055mmHg at 25°C
• Refractive Index: 1.658
• Storage Temp.: 2-8°C
• PKA: -5.29±0.30(Predicted)
• CAS DataBase Reference: 5-NITRO-1,2-BENZISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NITRO-1,2-BENZISOXAZOLE(39835-28-4)
• EPA Substance Registry System: 5-NITRO-1,2-BENZISOXAZOLE(39835-28-4)

Safety Data

• Hazardous Substances Data: 39835-28-4(Hazardous Substances Data)

Usage

General Description

5-NITRO-1,2-BENZISOXAZOLE is a chemical compound with the molecular formula C7H4N2O3. It is a nitro-substituted heterocyclic compound that is used in the synthesis of various pharmaceuticals and organic compounds. This chemical is also known for its antimicrobial and antiviral properties, which make it a potential candidate for drug development. 5-NITRO-1,2-BENZISOXAZOLE is considered to be a hazardous substance and should be handled with care due to its potential toxicity and environmental impact. It should be stored and used in accordance with strict safety regulations to minimize the risk of exposure.

InChI:InChI=1/C7H4N2O3/c10-9(11)6-1-2-7-5(3-6)4-8-12-7/h1-4H

Upstream product

• 97-51-8 5-Nitrosalicylaldehyde 
• 1595-15-9 2-hydroxy-5-nitro-benzaldehyde oxime 
• 271-95-4 1,2-benzisoxazole 

Downstream Products

• 16331-61-6 5-Nitro-N-ethyl-salicylamid 
• 239097-74-6 benzo[d]-isoxazol-5-amine 
• 39835-09-1 5-nitro-2-hydroxybenzonitrile 
• 39835-14-8 2-hydroxy-4-nitro-benzonitrile 

Relevant articles and documents

Interconnectivity between Surface Reactivity and Self-Assembly of Kemp Elimination Catalyzing Nanorods

Understanding the fundamental facts behind dynamicity of catalytic processes has been a longstanding quest across disciplines. Herein, we report self-assembly of catalytically active gold nanorods that can be regulated by tuning its reactivity towards a p

Utility of Nitrogen Extrusion of Azido Complexes for the Synthesis of Nitriles, Benzoxazoles, and Benzisoxazoles

The utility of the nitrogen extrusion reaction of azido complexes, generated in situ from the corresponding aldehydes or ketones with TMSN3 in the presence of ZrCl4 or TfOH, has been described. These azido complexes could undergo three different pathways, depending on the substrates. First, azido methanolate complexes or imine diazonium ions could lead to benzisoxazole products via an intramolecular nucleophilic substitution. Second, imine diazonium ions could also undergo either the elimination of proton to provide nitrile products in good to excellent yields or an aryl migration, followed by an intramolecular nucleophilic addition, to give benzoxazole products in good yields.

Bacterial siderophores: Synthesis and biological activities of novel pyochelin analogues

The synthesis and biological activities of four pyochelin analogues substituted in different parts of the molecule are reported: 5-NHBoc-pyochelin, 3″N-Boc-pyochelin, 3″-nor-NH-pyochelin and neopyochelin II, the enantiomer of natural pyochelin. All these