39860-12-3

Basic information

• Product Name: 1,5-dimethylbenzoimidazol-2-amine
• Synonyms: 1,5-dimethylbenzoimidazol-2-amine;1H-Benzimidazol-2-amine,1,5-dimethyl-(9CI);1,5-DIMETHYL-2-AMINOBENZIMIDAZOLE;1,5-Dimethyl-1H-benzimidazol-2-amine;1H-Benzimidazol-2-amine, 1,5-dimethyl-;Brn 0880435;Ccris 4361;1,5-DiMethyl-1H-benzo[d]iMidazol-2-aMine
• CAS NO: 39860-12-3
• Molecular Formula: C₉H₁₁N₃
• Molecular Weight: 161.21
• Product Categories: BENZIMIDAZOLE
• Mol File: 39860-12-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 232-233 °C(Solv: water (7732-18-5))
• Boiling Point: 348.1°C at 760 mmHg
• Flash Point: 164.3°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 5.14E-05mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.27±0.10(Predicted)
• CAS DataBase Reference: 1,5-dimethylbenzoimidazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-dimethylbenzoimidazol-2-amine(39860-12-3)
• EPA Substance Registry System: 1,5-dimethylbenzoimidazol-2-amine(39860-12-3)

Safety Data

• Hazardous Substances Data: 39860-12-3(Hazardous Substances Data)

Usage

General Description

1,5-dimethylbenzoimidazol-2-amine is a type of chemical compound that is also known as DMBA. It is an azo compound with a molecular formula C10H12N2. DMBA is an aromatic amine and has been used in various chemical and pharmaceutical applications. It is commonly used in the synthesis of dyes and pigments, as well as in the production of pharmaceutical drugs. DMBA is also known to exhibit certain biological activities, including anti-inflammatory and antimicrobial properties, making it a potentially important compound in the field of medicine and drug development. Overall, 1,5-dimethylbenzoimidazol-2-amine is a versatile chemical with various uses and potential biomedical applications.

InChI:InChI=1/C9H11N3/c1-6-3-4-8-7(5-6)11-9(10)12(8)2/h3-5H,1-2H3,(H2,10,11)

Upstream product

• 506-68-3 bromocyane 
• 39513-19-4 2-amino-4-methyl-N-methylaminobenzene 
• 4600-08-2 4,N-dimethyl-2-nitroaniline 
• 89-60-1 1-chloro-4-methyl-2-nitro-benzene 

Downstream Products

• 53182-58-4 (1,5-dimethyl-1H-benzoimidazol-2-yl)-nitroso-amine 

Relevant articles and documents

Discovery of 2-iminobenzimidazoles as potent hepatitis C virus inhibitors with a novel mechanism of action

In this report we describe 2-iminobenzimidazole (IBI) analogs, identified during the course of a phenotypic high-throughput screening campaign, as novel hepatitis C virus (HCV) inhibitors. A series of IBI derivatives was synthesized and evaluated for their inhibitory activity against infectious HCV. Among the IBIs derivatives studied in this work, we identified promising compounds with high antiviral efficacy, high selectivity index and good microsomal stability. Noteworthy, the IBI series exhibited inhibitory activity on early and late steps of the viral cycle, but not in the HCV replicon system demonstrating a mechanism of action distinct from clinical-stage and approved anti-HCV drugs. Overall, our results suggest that IBIs are predestinated for further exploration as lead compounds for novel HCV interventions.