399-77-9 Usage
General Description
1H-Benzimidazole, 5-methyl-2-(trifluoromethyl)-(9CI) is a chemical compound with the molecular formula C10H7F3N2. It is a derivative of benzimidazole with a methyl group and a trifluoromethyl group attached to the carbon atoms. 1H-Benzimidazole,5-methyl-2-(trifluoromethyl)-(9CI) is commonly used in organic synthesis and pharmaceutical research due to its unique structure and potential pharmacological properties. It may also have applications in the agrochemical industry. As a trifluoromethyl derivative, it is known for its high electronegativity and lipophilicity, which can influence its reactivity and bioavailability in various chemical and biological systems. However, further research is needed to fully understand its potential uses and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 399-77-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 399-77:
(5*3)+(4*9)+(3*9)+(2*7)+(1*7)=99
99 % 10 = 9
So 399-77-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7F3N2/c1-5-2-3-6-7(4-5)14-8(13-6)9(10,11)12/h2-4H,1H3,(H,13,14)
399-77-9Relevant articles and documents
Fe(OTf)3-catalyzed practical synthesis of 2-trifluoromethylarylimidazoles from o-arylenediamines and hexafluoroacetylacetone
Zhou, Yanmei,Shen, Guanshuo,Sui, Yuebo,Zhou, Haifeng
supporting information, p. 3396 - 3399 (2016/07/11)
An iron-catalyzed practical synthesis of 2-trifluoromethylarylimidazoles through condensation of o-arylenediamines and hexafluoroacetylacetone followed by intramolecular addition and C–C bond cleavage in one-pot has been developed. A series of title compounds were obtained with up to 99% yield. This method is quite practical and suitable for scalable preparation due to simple experimental procedure and readily available reagents.
