39977-58-7 Usage
Description
(2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine is a chemical compound belonging to the dihydropyridine family. It features a chloro(nitroso)methylidene group, which enhances its reactivity and potential applications in organic synthesis. Known for their diverse biological activities, dihydropyridines have been extensively studied for their roles as calcium channel blockers, antioxidants, and anti-cancer agents. This specific compound, due to its unique structure and potential pharmacological activities, may have significant applications in medicinal chemistry and drug development. Further research is necessary to fully explore its properties and possible uses.
Uses
Used in Medicinal Chemistry:
(2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its reactivity and unique structural features.
Used in Drug Development:
As a member of the dihydropyridine family, (2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine is used as a potential candidate for developing new drugs, particularly in the areas of cardiovascular health, as calcium channel blockers, and in cancer therapy, as an anti-cancer agent.
Used in Organic Synthesis:
(2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine is utilized as a reactive building block in organic synthesis for creating a variety of complex organic molecules, taking advantage of its chloro(nitroso)methylidene group.
Used in Antioxidant Research:
Given the antioxidant properties associated with dihydropyridines, (2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine is used as a subject of study in antioxidant research to explore its potential in combating oxidative stress and related diseases.
Used in Cancer Research:
(2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine is employed in cancer research as a potential anti-cancer agent, with the aim of understanding its effects on various types of cancer and its mechanisms of action.
Further research is essential to determine the full scope of applications and the safety and efficacy of (2E)-2-[chloro(nitroso)methylidene]-1,2-dihydropyridine in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 39977-58-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,9,7 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 39977-58:
(7*3)+(6*9)+(5*9)+(4*7)+(3*7)+(2*5)+(1*8)=187
187 % 10 = 7
So 39977-58-7 is a valid CAS Registry Number.
39977-58-7Relevant articles and documents
5-Substituted pyridylisoxazoles as effective inhibitors of platelet aggregation
Demina,Khodonov,Sinauridze,Shvets,Varfolomeev
, p. 2092 - 2113 (2015/06/08)
A series of 5-substituted 3-pyridylisoxazoles were synthesized using [3+2] cycloaddition of nitrile oxides to alkynes with variation of substituents at position 5 of the isoxazole ring without additional synthetic stages and with retention of 2-pyridyl-, 3-pyridyl, and 4-pyridyl substituents at position 3 of the isoxazole ring. Substituted pyridylisoxazoles are the potential antiaggregatory agents showing in vitro activity in the concentration range from 1?10-6 mol L-1 to 1?10-4 mol L-1 toward the human platelet rich blood plasma with arachidonic acid being used as the inductor of aggregation. These compounds do not act as cyclooxygenase or thromboxane synthase inhibitors, nor as thrombin inhibitors.
