39996-44-6

Basic information

• Product Name: 1-amino-3-cyanopyridin-1-ium 2,4,6-trimethylbenzenesulfonate
• CAS NO: 39996-44-6
• Molecular Weight: 319.384
• Mol File: 39996-44-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-amino-3-cyanopyridin-1-ium 2,4,6-trimethylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-amino-3-cyanopyridin-1-ium 2,4,6-trimethylbenzenesulfonate(39996-44-6)
• EPA Substance Registry System: 1-amino-3-cyanopyridin-1-ium 2,4,6-trimethylbenzenesulfonate(39996-44-6)

Safety Data

• Hazardous Substances Data: 39996-44-6(Hazardous Substances Data)

Upstream product

• 36016-39-4 N-(tert-butoxycarbonyl)-O-(mesitylsulfonyl)hydroxylamine 
• 100-54-9 pyridine-3-carbonitrile 
• 36016-40-7 mesitylenesulfonylhydroxylamine 

Relevant articles and documents

Regioselective Synthesis of Pyrazolo[1,5- a]pyridine via TEMPO-Mediated [3 + 2] Annulation-Aromatization of N-Aminopyridines and α,β-Unsaturated Compounds

A TEMPO-mediated [3 + 2] annulation-aromatization protocol for the preparation of pyrazolo[1,5-a]pyridines from N-aminopyridines and α,β-unsaturated compounds was developed. The procedure offered multisubstituted pyrazolo[1,5-a]pyridines in good to excellent yield with high and predictable regioselectivity. The modification of marketed drugs including Loratadine, Abiraterone, and Metochalcone, and a one-pot three-step gram scale synthesis of key intermediate for the preparation of Selpercatinib were demonstrated. Mechanism studies show that TEMPO serves both as a Lewis acid and as an oxidant.