400063-27-6

Basic information

• Product Name: 3-[(2-aminoethyl)sulfanyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione
• Synonyms: 2,5-Pyrrolidinedione, 3-[(2-aminoethyl)thio]-1-(4-fluorophenyl)-; 3-(2-Amino-ethylsulfanyl)-1-(4-fluoro-phenyl)-pyrrolidine-2,5-dione; 3-[(2-Aminoethyl)sulfanyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione
• CAS NO: 400063-27-6
• Molecular Formula: C12H13FN2O2S
• Molecular Weight: 268.3072
• Mol File: 400063-27-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 529.8°C at 760 mmHg
• Flash Point: 274.2°C
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 2.62E-11mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 3-[(2-aminoethyl)sulfanyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2-aminoethyl)sulfanyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione(400063-27-6)
• EPA Substance Registry System: 3-[(2-aminoethyl)sulfanyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione(400063-27-6)

Safety Data

• Hazardous Substances Data: 400063-27-6(Hazardous Substances Data)

Usage

Description

3-(2-Aminoethylsulfanyl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione, also known as BMS-267231, is a pyrrolidine derivative with potential pharmaceutical properties. It features an aminoethylsulfanyl group, a fluorophenyl group, and a pyrrolidine-2,5-dione ring structure. 3-(2-Aminoethylsulfanyl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione has been studied for its potential as a serotonin 5-HT1A receptor agonist and has shown promising results in preclinical studies for the treatment of anxiety and depression. Furthermore, it has been investigated for its potential to modulate the release of dopamine and norepinephrine in the central nervous system, suggesting potential therapeutic applications in neuropsychopharmacology.

Uses

Used in Pharmaceutical Industry:
3-(2-Aminoethylsulfanyl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione is used as a serotonin 5-HT1A receptor agonist for its potential role in treating anxiety and depression. Its mechanism of action involves modulating the release of neurotransmitters such as dopamine and norepinephrine in the central nervous system, which can contribute to the alleviation of symptoms associated with these conditions.
Used in Neuropharmacology Research:
In the field of neuropharmacology, 3-(2-Aminoethylsulfanyl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione serves as a compound of interest for studying the interactions between neurotransmitter systems and mental health disorders. Its potential to modulate neurotransmitter release makes it a valuable tool for understanding the complex interplay between serotonin, dopamine, and norepinephrine in the context of anxiety and depression.

InChI:InChI=1/C12H13FN2O2S/c13-8-1-3-9(4-2-8)15-11(16)7-10(12(15)17)18-6-5-14/h1-4,10H,5-7,14H2