40058-13-7

Basic information

• Product Name: cis-2-dimethylamino-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholane
• CAS NO: 40058-13-7
• Molecular Weight: 238.269
• Mol File: 40058-13-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: cis-2-dimethylamino-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholane(CAS DataBase Reference)
• NIST Chemistry Reference: cis-2-dimethylamino-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholane(40058-13-7)
• EPA Substance Registry System: cis-2-dimethylamino-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholane(40058-13-7)

Safety Data

• Hazardous Substances Data: 40058-13-7(Hazardous Substances Data)

Upstream product

• 50-98-6 ephedrine hydrochloride 
• 1608-26-0 Hexamethylphosphorous triamide 
• 299-42-3 ephedrine 
• 90-82-4 pseudoephedrine 

Downstream Products

• 40058-14-8 (2R,3S,7S,8R)-3,4,8-Trimethyl-2,7-diphenyl-1,6-dioxa-4,9-diaza-5λ⁵-phospha-spiro[4.4]nonane 
• 40058-14-8 (2R,3S,7S,8R)-3,4,8-Trimethyl-2,7-diphenyl-1,6-dioxa-4,9-diaza-5λ⁵-phospha-spiro[4.4]nonane 
• 50991-20-3 C₁₇H₂₁N₂O₂P 
• 50991-20-3 C₁₇H₂₁N₂O₂P 
• 27429-81-8 C₁₆H₁₉N₂O₂P 
• 27429-81-8 C₁₆H₁₉N₂O₂P 

Relevant articles and documents

Stereochemistry of Substitution at Trico-ordinate Phosphorus

A series of reactions of ring-substituted 1,3,2-dioxaphospholanes, 1,3,2-oxazaphospholanes, 1,2-oxaphospholes, and phosphetanes bearing the leaving groups Cl, OR, or NR2 on phosphorus, with the nucleophiles HCl, MeO-, MeOH, PhOH, Me2NH, Et2NH, and 5NH have been studied.N.m.r. signals (1H and 31P) from reactant and product diastereoisomers have been assigned, and the stereochemistry of the substitution reactions have been determined by 31P n.m.r. monitoring.The outcome varies from complete inversion to complete lack of stereoselectivity.During the initial stages many of the non-selective reactions proceed with predominant inversion, and most of the results may be interpreted by assuming that the actual substitution step occurs with inversion, and that the lack of stereoselectivity is due to competing isomerizations of products or reactants.Exceptions are certain reactions where the leaving group is Cl; these appear to involve a non-selective substitution step.