40061-50-5

Basic information

• Product Name: 2-(4-methanesulfonyl-phenyl)-1-pyridin-3-yl-ethanone
• Synonyms: 2-(4-methanesulfonyl-phenyl)-1-pyridin-3-yl-ethanone
• CAS NO: 40061-50-5
• Molecular Weight: 275.328
• Mol File: 40061-50-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(4-methanesulfonyl-phenyl)-1-pyridin-3-yl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methanesulfonyl-phenyl)-1-pyridin-3-yl-ethanone(40061-50-5)
• EPA Substance Registry System: 2-(4-methanesulfonyl-phenyl)-1-pyridin-3-yl-ethanone(40061-50-5)

Safety Data

• Hazardous Substances Data: 40061-50-5(Hazardous Substances Data)

Upstream product

• 3360-71-2 diphenyl (phenylamino)(pyridin-3-yl)methylphosphonate 
• 100-68-5 methyl-phenyl-thioether 
• 5398-77-6 para-methanesulfonylbenzaldehyde 
• 40061-49-2 2-(4-methylsulfanyl-phenyl)-1-pyridin-3-yl-ethanone 
• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 90536-66-6 4-(methylsulfonyl)phenylacetic acid 

Downstream Products

• 481679-80-5 C₃₄H₃₂N₂O₅S₂ 
• 202409-31-2 5-Chloro-3-(4-(methylsulfonyl)phenyl)-2-(3-pyridinyl)pyridine 

Relevant articles and documents

PROCESS FOR MAKING 2-ARYL-3-ARYL-5-HALO PYRIDINES USEFUL AS COX-2 INHIBITORS

The invention encompasses a process for making compounds of Formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases.

Substituted pyridines as selective cyclooxygenase-2 inhibitors

The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.