400629-31-4Relevant articles and documents
Synthesis and evaluation of new benzimidazole-based COX inhibitors: A naproxen-like interaction detected by STD-NMR
Carvalho, Luísa C. R.,Ribeiro, Daniela,Seixas, Raquel S. G. R.,Silva, Artur M. S.,Nave, Mariana,Martins, Ana C.,Erhardt, Stefan,Fernandes, Eduarda,Cabrita, Eurico J.,Marques, M. Manuel B.
, p. 49098 - 49109 (2015)
Non-steroidal anti-inflammatory drugs exert their pharmacological activity through inhibition of cyclooxygenase 1 and 2 (COX-1 and COX-2). Recent research suggests that a balanced inhibition of both COX-1 and COX-2 is the key to reduce the side-effects ex
