400769-77-9

Basic information

• Product Name: D-Glutamic acid, 4-hydroxy-4-(1H-indol-3-ylmethyl)-, (4S)-
• CAS NO: 400769-77-9
• Molecular Formula: C14H16N2O5
• Molecular Weight: 292.291
• Mol File: 400769-77-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: D-Glutamic acid, 4-hydroxy-4-(1H-indol-3-ylmethyl)-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: D-Glutamic acid, 4-hydroxy-4-(1H-indol-3-ylmethyl)-, (4S)-(400769-77-9)
• EPA Substance Registry System: D-Glutamic acid, 4-hydroxy-4-(1H-indol-3-ylmethyl)-, (4S)-(400769-77-9)

Safety Data

• Hazardous Substances Data: 400769-77-9(Hazardous Substances Data)

Upstream product

• 855433-72-6 4-amino-2-hydroxy-2-(1H-indol-3-ylmethyl)-pentanedioic acid 

Downstream Products

• 400769-81-5 (2R,4R)-2-((1H-indol-3-yl)methyl)-4-amino-2-hydroxypentane-1,5-dioic acid 
• 146142-94-1 (2S,4S)-2-((1H-indol-3-yl)methyl)-4-amino-2-hydroxypentane-1,5-dioic acid 

Relevant articles and documents

PRODUCTION OF MONATIN ENANTIOMERS

Methods for the preparation of the high intensity sweetener, monatin, 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)indole, its salts and internal condensation products thereof, including methods applicable to the large-scale production of monatin are described.

PROCESS FOR PRODUCING MONATIN

By simultaneously carrying out an isomerization reaction at position 2 of monatin in different configurations at positions 2 and 4 in the presence of an aldehyde under a condition of pH 4 to 11 in a mixture solvent of water and an organic solvent, and the crystallization of monatin in the same configurations at positions 2 and 4 or a salt thereof, monatin useful as a sweetener, particularly optically active monatin can efficiently be produced.