40108-73-4Relevant articles and documents
Lorberth
, p. 159,164 (1974)
Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties
Gagnot, Glwadys,Hervin, Vincent,Coutant, Eloi P.,Goyard, Sophie,Jacob, Yves,Rose, Thierry,Hibti, Fatima Ezzahra,Quatela, Alessia,Janin, Yves L.
supporting information, p. 2112 - 2123 (2020/12/18)
In this work on the design and studies of luciferins related to the blue-hued coelenterazine, the synthesis of heterocyclic analogues susceptible to produce a photon, possibly at a different wavelength, is undertaken. Here, the synthesis of O-acetylated derivatives of imidazo[1,2-b]pyridazin-3(5 H)-one, imidazo[2,1-f][1,2,4]triazin-7(1 H)-one, imidazo[1,2-a]pyridin-3-ol, imidazo[1,2-a]quinoxalin-1(5 H)-one, benzo[f]imidazo[1,2-a]quinoxalin-3(11 H)-one, imidazo[1′,2′:1,6]pyrazino[2,3-c]quinolin-3(11 H)-one, and 5,11-dihydro-3 H-chromeno[4,3-e]imidazo[1,2-a]pyrazin-3-one is described thanks to extensive use of the Buchwald–Hartwig N-arylation reaction. The acidic hydrolysis of these derivatives then gave solutions of the corresponding luciferin analogues, which were studied. Not too unexpectedly, even if these were “dressed” with substituents found in actual substrates of the nanoKAZ/NanoLuc luciferase, no bioluminescence was observed with these compounds. However, in a phosphate buffer, all produced a light signal, by chemiluminescence, with extensive variations in their respective intensity and this could be increased by adding a quaternary ammonium salt in the buffer. This aspect was actually instrumental to determine the emission spectra of many of these luciferin analogues.
Blue light electroluminescent material and application thereof
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, (2020/01/25)
The invention relates to a blue light electroluminescent material and an application thereof. A structural formula of the blue light electroluminescent material is represented by a chemical formula 1shown in the specification. The blue light electroluminescent material provided by the invention has the advantages of high luminous efficiency, high color saturation, good film-forming performance, better thermal stability and the like; compared with a conventional blue host material, the blue light electroluminescent material provided by the invention has the characteristics of high luminous efficiency and long service life of a prepared device; and inventors also find that when a deuterium element is introduced into the material structure, by using the characteristics of the deuterium element, the quantum efficiency, color saturation, service life and the like can be improved, and at the same time, the material has higher tolerance when used for preparing the device.