40115-02-4Relevant articles and documents
Photoelectrochemical cross-dehydrogenative coupling of benzothiazoles with strong aliphatic C-H bonds
Capaldo, Luca,Quadri, Lorenzo L.,Merli, Daniele,Ravelli, Davide
, p. 4424 - 4427 (2021/05/10)
A photoelectrochemical strategy for the cross-dehydrogenative coupling of unactivated aliphatic hydrogen donors (e.g.alkanes) with benzothiazoles is reported. We used tetrabutylammonium decatungstate as the photocatalyst to activate strong C(sp3)-H bonds in the chosen substrates, while electrochemistry scavenged the extra electrons.
Desulfonative photoredox alkylation of: N -heteroaryl sulfones-an acid-free approach for substituted heteroarene synthesis
Wang, Zheng-Jun,Zheng, Shuai,Matsui, Jennifer K.,Lu, Zhipeng,Molander, Gary A.
, p. 4389 - 4393 (2019/04/29)
Minisci-type alkylation of electron-deficient heteroarenes has been a pivotal technique for medicinal chemists in the synthesis of drug-like molecules. However, such transformations usually require harsh conditions (e.g., strong acids, stoichiometric amou
Mn(II)-catalyzed C-H alkylation of imidazopyridines and N-heteroarenes via decarbonylative and cross-dehydrogenative coupling
Samanta, Sadhanendu,Hajra, Alakananda
, p. 4363 - 4371 (2019/03/26)
A Mn(II)-catalyzed efficient C-H alkylation of imidazoheterocycles and N-heteroarenes with aliphatic aldehydes has been developed via oxidative decarbonylation. Other alkylating agents such as cyclic alkanes, ethers, and alcohols also coupled with N-heteroarenes through cross-dehydrogenative coupling. Regioselectively C5-alkylated imidazoheterocycles were synthesized in good yields. Experimental results show that radical pathway might be involved in this reaction.