40117-92-8 Usage
Description
1-BENZYL-4-CARBOXYMETHYL-PIPERIDINE-4-CARBOXYLIC ACID is a complex chemical compound that features a benzyl group, a piperidine ring, and two carboxylic acid groups. It is a carboxylic acid derivative of piperidine, a heterocyclic amine. 1-BENZYL-4-CARBOXYMETHYL-PIPERIDINE-4-CARBOXYLIC ACID holds potential in medicinal chemistry, particularly for the development of pharmaceuticals aimed at the central nervous system. Its distinctive structural attributes and functional groups render it a valuable component for the synthesis of novel drug candidates and chemical probes. 1-BENZYL-4-CARBOXYMETHYL-PIPERIDINE-4-CARBOXYLIC ACID's structure also suggests it may possess significant pharmacological properties, positioning it as a promising substance for ongoing research and development.
Uses
Used in Pharmaceutical Industry:
1-BENZYL-4-CARBOXYMETHYL-PIPERIDINE-4-CARBOXYLIC ACID is used as a building block for the synthesis of new drug candidates due to its unique structure and functional groups that can be leveraged to create compounds with potential therapeutic effects on the central nervous system.
Used in Medicinal Chemistry Research:
1-BENZYL-4-CARBOXYMETHYL-PIPERIDINE-4-CARBOXYLIC ACID is used as a chemical probe for studying the interactions and mechanisms related to the central nervous system, potentially leading to the discovery of new treatments for neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 40117-92-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,1,1 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40117-92:
(7*4)+(6*0)+(5*1)+(4*1)+(3*7)+(2*9)+(1*2)=78
78 % 10 = 8
So 40117-92-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H19NO4/c17-13(18)10-15(14(19)20)6-8-16(9-7-15)11-12-4-2-1-3-5-12/h1-5H,6-11H2,(H,17,18)(H,19,20)
40117-92-8Relevant articles and documents
SELF-IMMOLATIVE LINKERS CONTAINING MANDELIC ACID DERIVATIVES, DRUG-LIGAND CONJUGATES FOR TARGETED THERAPIES AND USES THEREOF
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, (2015/03/28)
The invention provides a therapeutic drug and targeting conjugate, pharmaceutical compositions containing these conjugates in pharmaceutical composition, and uses of these conjugates in anti-neoplastic and other therapeutic regimens. Also provided are novel intermediates thereof. The conjugates provide a therapeutic drug fragment or prodrug fragment bound to a targeting moiety via a linker which comprises a substrate cleavable by a protease such as Cathepsin B. The targeting moiety is a ligand which targets a cell surface molecule, such as a cell surface receptor on an anti-neoplastic cell. The ligand may function solely as a targeting moiety or may itself have a therapeutic effect. Following administration of the therapeutic drug and targeting conjugate of formula I and exposure of the conjugate to the protease specific for the substrate, the linker is cleaved and the targeting moiety is separated from the conjugate, which causes the drug fragment or prodrug fragment to convert to the drug or prodrug. The recited conjugates are useful in anti-neoplastic therapies. Also provided are methods of making the therapeutic drug and targeting conjugates and intermediates thereof, and kits comprising the therapeutic drug and targeting conjugates.