40137-12-0

Basic information

• Product Name: Phosphonic acid, [[(4-chlorophenyl)sulfonyl]methyl]-, diethyl ester
• CAS NO: 40137-12-0
• Molecular Formula: C11H16ClO5PS
• Molecular Weight: 326.738
• Mol File: 40137-12-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [[(4-chlorophenyl)sulfonyl]methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [[(4-chlorophenyl)sulfonyl]methyl]-, diethyl ester(40137-12-0)
• EPA Substance Registry System: Phosphonic acid, [[(4-chlorophenyl)sulfonyl]methyl]-, diethyl ester(40137-12-0)

Safety Data

• Hazardous Substances Data: 40137-12-0(Hazardous Substances Data)

Upstream product

• 31618-90-3 diethyl (p-toluenesulfonyloxymethane)phosphonate 
• 3084-40-0 diethyl (1-hydroxymethyl)phosphonate 
• 69770-58-7 diethyl<<(p-chlorophenyl)sulfide>methyl>phosphonate 

Downstream Products

• 40582-76-1 p-Chlorphenyl-3-phenyl-1-butenyl-sulfon 
• 79328-75-9 1-Chloro-4-[((E)-tridec-1-ene)-1-sulfonyl]-benzene 
• 16215-12-6 (E)-1-chloro-4-(styrylsulfonyl)benzene 
• 40582-81-8 p-Chlorphenyl-2-methyl-1-heptenyl-sulfon 
• 6178-26-3 (E)-4-chlorostyryl 4-chlorophenyl sulfone 
• 76859-78-4 (E)-1-(2-((4-chlorophenyl)sulfonyl)vinyl)-3-chlorobenzene 
• 56267-73-3 (E)-1-(2-((4-chlorophenyl)sulfonyl)vinyl)-4-fluorobenzene 
• 1554271-57-6 (E)-1-(2-((4-chlorophenyl)sulfonyl)vinyl)-3-fluorobenzene 
• 1554271-53-2 (E)-1-(2-((4-chlorophenyl)sulfonyl)vinyl)-4-trifluoromethylbenzene 
• 1554271-50-9 (E)-1-(2-((4-chlorophenyl)sulfonyl)vinyl)-3-trifluoromethylbenzene 
• 1554271-49-6 (E)-1-(2-((4-chlorophenyl)sulfonyl)vinyl)-2-trifluoromethylbenzene 
• 40583-04-8 p-Chlorphenyl-2-(3-aethoxycarbonylcyclohexyl)-propyl-sulfon 
• 40583-05-9 p-Chlorphenyl-2-(3-aethoxycarbonylcyclohexyl)-hexyl-sulfon 

Relevant articles and documents

Conjugate Addition Reactions of α,β-Unsaturated Ketones with Higher Order, Mixed Organocuprate Reagents, R2Cu(CN)Li2

Conjugate reactions of mixed cuprates R2Cu(CN)Li2 with α,β-unsaturated ketones are reported.These reagents, in most cases, react extremely rapidly affording the corresponding alkylated ketones in high yields.Attempts at trapping the intermediate enolates appeared to be successful using MeI as electrophile; however, the method is not general and was, therefore, not pursued.The effects of solvent and ligand composition on R2Cu(CN)Li2 as well as on the more highly mixed species RTRRCu(CN)Li2 have been examined.The selectivity of ligand transfer in these latter,second generation organocuprates is also discussed.

NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF

The present invention relates to a novel halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative or a pharmaceutically acceptable salt thereof; a preparation method thereof; and an Nrf2 activator and a pharmaceutical composition for preventing or treating diseases induced by a decrease in Nrf2 activity, both of which comprise the same as an active ingredient.