401575-24-4 Usage
Description
2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96% is a white crystalline solid chemical compound commonly utilized in organic synthesis and pharmaceutical research. With a purity of 96%, it features a trifluoromethyl group and a pyridylmethyl group, which endow it with unique properties and reactivity. This makes it a valuable building block for the synthesis of complex organic molecules and pharmaceutical intermediates, suitable for various laboratory applications.
Uses
Used in Organic Synthesis:
2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96% is used as a building block for the synthesis of complex organic molecules due to its unique properties and reactivity.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96% is used as a key intermediate in the development of new drugs, contributing to the advancement of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 401575-24-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,5,7 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 401575-24:
(8*4)+(7*0)+(6*1)+(5*5)+(4*7)+(3*5)+(2*2)+(1*4)=114
114 % 10 = 4
So 401575-24-4 is a valid CAS Registry Number.
401575-24-4Relevant articles and documents
Distorted Copper(II) Complex with Unusually Short CF···Cu Distances
Cody, Claire C.,Kelly, H. Ray,Mercado, Brandon Q.,Batista, Victor S.,Crabtree, Robert H.,Brudvig, Gary W.
supporting information, p. 14759 - 14764 (2021/10/12)
We find a Cu(II)-(L-CF3)2 complex (L-CF3 = 2,2,2-trifluoro-N-[2-(pyridin-2-yl)propan-2-yl]acetamide) with a distorted seesaw geometry. It has the shortest crystallographic CF···Cu distances yet reported, to the best of our knowledge (?), for which computational and experimental data indicate a secondary bonding interaction. A comparison with a CCl3 version and one without ligand backbone gem-dimethyl groups suggests a steric origin for the distorted geometry, resulting from the specific ligand interactions.
Efficient Preparation of Imidazo[1,5- a ]pyridine-1-carboxylic Acids
Tverdiy, Dmytro O.,Chekanov, Maksym O.,Savitskiy, Pavlo V.,Syniugin, Anatolii R.,Yarmoliuk, Sergiy M.,Fokin, Andrey A.
, p. 4269 - 4277 (2016/11/26)
We report a novel and efficient approach to the synthesis of imidazo[1,5-a]pyridine-1-carboxylic acids. By using the reaction of 2-(aminomethyl)pyridine with acyl chlorides followed by one-pot treatment with trifluoroacetic anhydride, 2,2,2-trifluoro-1-im