402-61-9 Usage
Description
5-Methyl-1H-pyrazole-3-carboxylic acid is a member of the pyrazole class, characterized by the presence of a methyl and carboxylic acid group substituents at positions 5 and 3, respectively. It is a white to light yellow solid and is known for its potent and selective inhibition of D-amino acid oxidase (DAO), also known as DAAO, DAMOX, and OXDA.
Uses
Used in Pharmaceutical Applications:
5-Methyl-1H-pyrazole-3-carboxylic acid is used as a pharmaceutical agent for its potent and selective inhibition of D-amino acid oxidase (DAO). This inhibition protects DAO cells from oxidative stress induced by D-Serine, making it a potential candidate for the development of treatments targeting conditions related to DAO dysregulation.
Used in Pain Management:
In the field of pain management, 5-Methyl-1H-pyrazole-3-carboxylic acid is used as an analgesic agent. It specifically prevents formalin-induced tonic pain, which is a type of persistent pain that can be challenging to treat. Its ability to target and alleviate this type of pain makes it a valuable compound in the development of novel pain management therapies.
Used in Chemical Research:
5-Methyl-1H-pyrazole-3-carboxylic acid is also utilized in chemical research as a starting material or intermediate for the synthesis of various compounds with potential applications in different industries, including pharmaceuticals, agrochemicals, and materials science. Its unique chemical properties and reactivity make it a versatile building block for the development of new molecules with specific functions and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 402-61-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 402-61:
(5*4)+(4*0)+(3*2)+(2*6)+(1*1)=39
39 % 10 = 9
So 402-61-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O2/c1-3-2-4(5(8)9)7-6-3/h2H,1H3,(H,6,7)(H,8,9)
402-61-9Relevant articles and documents
Strategy for the Synthesis of pyrazolo[5,1-d][1,2,5]triazepinones, a new heterocyclic system
Kharaneko
, p. 1322 - 1325 (2016)
A preparative procedure has been developed for the synthesis of 4-oxo-7-phenyl-5,8-dihydro-4H-pyrazolo[ 5,1-d][1,2,5]triazepine-2-carbohydrazide, the first representative of a new heterocyclic system, by recyclization of methyl 4-oxo-6-phenyl-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate with hydrazine hydrate.