402822-70-2Relevant articles and documents
Palladium-catalyzed R2(O)P directed C(sp2)-H acetoxylation
Zhang, Heng,Hu, Rong-Bin,Zhang, Xiao-Yu,Li, Shi-Xia,Yang, Shang-Dong
supporting information, p. 4686 - 4689 (2014/05/06)
A novel and efficient Pd-catalyzed C-H acetoxylation is described. The approach uses R2(O)P as a directing group to synthesize various substituted 2′-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields. This journal is the Partner Organisations 2014.
Palladium-catalysed synthesis of biaryl phosphines
Baillie, Colin,Xiao, Jianliang
, p. 4159 - 4168 (2007/10/03)
Monodentate, biphenyl-type phosphines have emerged as a powerful class of ligands in homogeneous catalysis. Synthetic methods for these ligands are limited, however. We report that the palladium-catalysed Suzuki coupling of OPR2(o-C6H4X) (R=Ph, t-Bu; X=Br, I) with arylboronic acids affords a variety of biaryl phosphine oxides including those that contain heterocycles. The corresponding phosphines are readily obtained by treatment with HSiCl3. The methodology provides an easy entry to monodentate biaryl and heterobiaryl Poverlapping logical AND signX (X=N, O, S) phosphines with diverse steric and electronic properties.