403706-60-5

Basic information

• Product Name: (S)-1-(furan-2-yl)-4-methyl-4-nitro-3-phenylpentan-1-one
• Synonyms: (S)-1-(furan-2-yl)-4-methyl-4-nitro-3-phenylpentan-1-one
• CAS NO: 403706-60-5
• Molecular Weight: 287.315
• Mol File: 403706-60-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-(furan-2-yl)-4-methyl-4-nitro-3-phenylpentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(furan-2-yl)-4-methyl-4-nitro-3-phenylpentan-1-one(403706-60-5)
• EPA Substance Registry System: (S)-1-(furan-2-yl)-4-methyl-4-nitro-3-phenylpentan-1-one(403706-60-5)

Safety Data

• Hazardous Substances Data: 403706-60-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 1777-60-2 [(furan-2-ylcarbonyl)methylene]triphenylphosphorane 
• 79-46-9 2-nitropropane 
• 3988-74-7 (E)-1-(furan-2-yl)-3-phenylprop-2-en-1-one 
• 3988-74-7 1-(2-furyl)-3-phenylpropen-1-one 

Relevant articles and documents

High pressure-assisted low-loading asymmetric organocatalytic conjugate addition of nitroalkanes to chalcones

The application of high pressure (up to 9 kbar) allows for relatively fast (1-5 h) and highly enantioselective 1,4-addition of nitromethane and 2-nitropropane to chalcones at room temperature with substantial reduction of catalyst loading (0.2-1 mol% of cinchona alkaloid-based thioureas and squaramides). Various γ-nitroketones were obtained at 9 kbar with high yield and enantioselectivity (up to 98%), whereas in control experiments at atmospheric pressure usually only a small amount (10%) of products were formed after 20 h.