40380-36-7

Basic information

• Product Name: 5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile
• Synonyms: 5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile;2,3-Dihydro-5,6-dimethyl-3-oxo-4-pyridazinecarbonitrile;4-Pyridazinecarbonitrile, 2,3-dihydro-5,6-dimethyl-3-oxo-;Nsc 338208;3-hydroxy-5,6-dimethylpyridazine-4-carbonitrile
• CAS NO: 40380-36-7
• Molecular Formula: C₇H₇N₃O
• Molecular Weight: 149.15
• Mol File: 40380-36-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 210-211 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.26g/cm³
• Refractive Index: 1.604
• PKA: 9.51±0.70(Predicted)
• CAS DataBase Reference: 5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile(40380-36-7)
• EPA Substance Registry System: 5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile(40380-36-7)

Safety Data

• Hazardous Substances Data: 40380-36-7(Hazardous Substances Data)

Usage

General Description

5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile is a chemical compound with the molecular formula C7H6N4O. It is a heterocyclic organic compound with a pyridazine core and a carbonitrile substituent. 5,6-dimethyl-3-oxo-2H-pyridazine-4-carbonitrile is commonly used as a building block for the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has applications in the pharmaceutical industry as a potential precursor for the development of new drugs and therapeutic agents. Additionally, it may also have uses in the field of materials science and organic synthesis due to its unique structural properties. However, as with any chemical compound, proper handling and storage are necessary to ensure safe use.

InChI:InChI=1/C7H7N3O/c1-4-5(2)9-10-7(11)6(4)3-8/h1-2H3,(H,10,11)

Upstream product

• 119248-33-8 3-(cyanoacetyl-hydrazono)-butan-2-one 
• 140-87-4 Cyanoacetohydrazide 
• 431-03-8 dimethylglyoxal 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 1452226-14-0 5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxylic acid 
• 1181626-76-5 1,3-diphenyl-2,2,4,4-tetrachloro-2,4-bis(4-cyano-5,6-dimethylpyridazin-3(2H)-one)cyclodiphosph(V)azane 
• 100114-19-0 5,6-dimethyl-2H-pyridazin-3-one 
• 873397-60-5 6-Chlor-3,4-dimethyl-pyridazin 
• 717840-52-3 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid [1-(4-nitro-phenyl)-meth-(Z)-ylidene]-hydrazide 
• 867350-44-5 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid [1-(4-chloro-phenyl)-meth-(Z)-ylidene]-hydrazide 
• 867350-37-6 2-(4-cyano-5,6-dimethyl-pyridazin-3-ylsulfanyl)-N-(4-methoxy-phenyl)-acetamide 
• 867350-36-5 2-(4-cyano-5,6-dimethyl-pyridazin-3-ylsulfanyl)-N-p-tolyl-acetamide 
• 93824-72-7 3-chloro-5,6-dimethylpyridazine-4-carbonitrile 

Relevant articles and documents

Synthesis of novel polyfunctionally substituted thieno[2,3-c]pyridazines

4-Cyano-5,6-dimethylpyridazin-3-(2H)-thione 3b was used as a key intermediate for the synthesis of novel polysubstituted thieno[2,3-c] pyridazines.

CCSO nano catalyzed solid phase synthesis of 3-oxo-5,6-disubstituted-2,3-dihydropyridazine-4-carbonitrile

Co-doped Ce0.94Ca0.05Sr0.01O1.94 (CCSO) nano particles have been successfully synthesized by an auto-combustion method and were characterized by XRD, TEM and AFM analyses. The catalytic activity of the nano-catalyst is evaluated by the synthesis of substituted pyridazines from substituted benzil and cyano acetylhydrazide, which have great biological and pharmaceutical interest. Thus, a highly economically efficient one-pot solvent free synthesis of pyridazine was developed, which is promoted by the CCSO nano catalyst. The benefits of the reaction are its very short time (2-4 min) and high yields (90-95%). The method offers a highly convergent, inexpensive, and functionality-tolerable procedure for rapid access to important pyridazine compounds in good yields. This journal is

Novel synthesis of thieno[2,3-c]pyridazine and pyrimido[4′,5′: 4,5]thieno[2,3-c]pyridazine derivatives

Novel series of thieno[2,3-c]pyridazines and pyrimido[4′,5′:4, 5] thieno-[2,3-c]pyridazines have been synthesized from the readily accessible 4-cyano-5,6-dimethylpyridazin-3(2H)-thione 3b. Copyright Taylor & Francis Inc.