403842-38-6 Usage
Description
2-(1-HEXYNYL)-N-METHYLADENOSINE, also known as HEMADO, is an organic compound that functions as a selective adenosine A3 receptor agonist. This means it has the ability to selectively bind to and activate the adenosine A3 receptor, which is involved in various physiological processes. 2-(1-HEXYNYL)-N-METHYLADENOSINE is characterized by its unique molecular structure, which includes a hexynyl group and a methyl group attached to an adenosine base.
Uses
Used in Pharmaceutical Industry:
HEMADO is used as a therapeutic agent for the treatment of inflammatory diseases such as asthma, ischemic injury, and cancer. The activation of adenosine A3 receptors by HEMADO can help modulate the immune response and reduce inflammation, making it a promising candidate for the development of new drugs to combat these conditions.
Used in Research Applications:
HEMADO is also used as a research tool in the study of adenosine receptor biology and the development of new drugs targeting these receptors. Its selective activation of the adenosine A3 receptor makes it a valuable compound for investigating the role of this receptor in various physiological processes and disease states.
Biological Activity
High affinity and selective adenosine A 3 receptor agonist (K i values are 1.1, 327, 1230 and > 30,000 nM for human A 3 , A 1 , A 2A and A 2B receptors respectively).
Check Digit Verification of cas no
The CAS Registry Mumber 403842-38-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,3,8,4 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 403842-38:
(8*4)+(7*0)+(6*3)+(5*8)+(4*4)+(3*2)+(2*3)+(1*8)=126
126 % 10 = 6
So 403842-38-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H23N5O4/c1-3-4-5-6-7-11-20-15(18-2)12-16(21-11)22(9-19-12)17-14(25)13(24)10(8-23)26-17/h9-10,13-14,17,23-25H,3-5,8H2,1-2H3,(H,18,20,21)/t10-,13?,14+,17-/m1/s1
