404-15-9 Usage
General Description
1-Acetoxy-4-fluorobenzene is a chemical compound with the molecular formula C8H7FO2. It is an aromatic organic compound with a benzene ring substituted by a fluorine atom and an acetoxy group. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a colorless liquid with a strong aromatic odor and is insoluble in water but soluble in organic solvents. 1-Acetoxy-4-fluorobenzene is also known by other names such as p-Fluoroacetophenone and 1-Acetyl-4-fluorobenzene. It is important to handle and use this chemical with caution, as it can be harmful if inhaled, ingested, or comes into contact with the skin.
Check Digit Verification of cas no
The CAS Registry Mumber 404-15-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 404-15:
(5*4)+(4*0)+(3*4)+(2*1)+(1*5)=39
39 % 10 = 9
So 404-15-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FO2/c1-6(10)11-8-4-2-7(9)3-5-8/h2-5H,1H3
404-15-9Relevant articles and documents
A new finding in selective Baeyer-Villiger oxidation of α-fluorinated ketones; a new and practical route for the synthesis of α-fluorinated esters
Kobayashi, Satoru,Tanaka, Hiroaki,Amii, Hideki,Uneyama, Kenji
, p. 1547 - 1552 (2007/10/03)
α-Fluorinated esters were effectively prepared by the Baeyer-Villiger oxidation of α-fluorinated ketones with m-chloroperbenzoic acid (m-CPBA) under mild conditions. The yield of the esters was influenced by the choice of solvent, base, and substituent on the aryl group of the ketones. 4-Methoxyphenyl substituted fluoroketones were oxidized almost quantitatively with m-CPBA within 10 min to 12 h at room temperature using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as a cosolvent with CH2Cl2 (1:1, v/v) and aqueous buffer (KH2PO4-NaOH, pH 7.6) as an additive base. The oxidation reaction rates of α-fluorinated ketones were higher than those of the corresponding non-fluorinated ketones. The fluorine atom at α-position of fluoromethyl aryl ketones enhanced the reactivity in the Baeyer-Villiger oxidation.