404-32-0

Basic information

• Product Name: Cbz-4-Fluoro-D-Phenylalanine
• Synonyms: Cbz-4-Fluoro-D-Phenylalanine;Cbz-D-Phe(4-F)-OH;4-Fluoro-N-[(phenylmethoxy)carbonyl]-DL-phenylalanine;4-Fluoro-N-Cbz-DL-phenylalanine
• CAS NO: 404-32-0
• Molecular Formula: C₁₇H₁₆FNO₄
• Molecular Weight: 317.3116432
• Mol File: 404-32-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cbz-4-Fluoro-D-Phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-4-Fluoro-D-Phenylalanine(404-32-0)
• EPA Substance Registry System: Cbz-4-Fluoro-D-Phenylalanine(404-32-0)

Safety Data

• Hazardous Substances Data: 404-32-0(Hazardous Substances Data)

Upstream product

• 127862-81-1 Z-DL-Phe(4F)-OCH₂CF₃ 
• 33208-99-0 (S)-alaninamide hydrochloride 
• 141971-11-1 Z-DL-Phe(4F)OMe 

Downstream Products

• 126689-29-0 [1-[N',N'-Bis-(2-chloro-ethyl)-hydrazinocarbonyl]-2-(4-fluoro-phenyl)-ethyl]-carbamic acid benzyl ester 
• 17193-32-7 2-amino-3-(4-fluorophenyl)propanamide 
• 18125-46-7 (R)-4-fluorophenylalanine 
• 1132-68-9 L-4-fluorophenylalanine 
• 141971-11-1 Z-DL-Phe(4F)OMe 
• 117402-85-4 L-Z-4-F-Phe-OEt 
• 117467-73-9 (R)-(N-benzyloxycarbonyl)-p-fluorophenylalanine 
• 126689-30-3 2-Amino-3-(4-fluoro-phenyl)-propionic acid N',N'-bis-(2-chloro-ethyl)-hydrazide; hydrobromide 

Relevant articles and documents

α-Chymotrypsin-catalysed peptide synthesis using activated esters as acyl donors

The coupling efficiency in α-chymotrypsin-catalysed peptide synthesis is greatly improved by the use of activated esters such as the 2,2,2-trifluoroethyl ester as acyl donor instead of the conventional methyl ester; this approach is useful for the incorporation of non-protein amino acids into peptides.